Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12494099 | 0.79 | ATM (0.43) | AR | |
| SCHEMBL12525439 | 0.78 | AR (0.31) | AR | |
| SCHEMBL29966221 | 0.78 | AR (0.31) | AR | |
| SCHEMBL12493739 | 0.74 | CYP1A2 (0.39) | — | |
| SCHEMBL12494859 | 0.70 | CYP2C19 (0.40) | TRPM5 | |
| SCHEMBL12528287 | 0.69 | AR (0.32) | AR | |
| SCHEMBL12527483 | 0.68 | RAB9A (0.44) | — | |
| SCHEMBL11939275 | 0.66 | CYP2C9 (0.39) | AR | |
| SCHEMBL31581299 | 0.66 | CYP2C9 (0.39) | AR | |
| SCHEMBL12494495 | 0.66 | POLB (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2683694-B1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | SUZHOU KINTOR PHARMACEUTICALS INC (CN) | 2016-04-27 | — | — | EP | disclosed |
| EP-2683694-B1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | SUZHOU KINTOR PHARMACEUTICALS INC (CN) | 2016-04-27 | — | — | EP | disclosed |
| US-9216957-B2 | Androgen receptor antagonists and uses thereof | SUZHOU KINTOR PHARMACEUTICALS, INC. (CN) | 2015-12-22 | — | — | US | disclosed |
| US-9216957-B2 | Androgen receptor antagonists and uses thereof | SUZHOU KINTOR PHARMACEUTICALS, INC. (CN) | 2015-12-22 | — | — | US | disclosed |
| US-20140066425-A1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | SUZHOU KINTOR PHARMACEUTICALS, INC. (CN) | 2014-03-06 | — | — | US | disclosed |
| US-20140066425-A1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | SUZHOU KINTOR PHARMACEUTICALS, INC. (CN) | 2014-03-06 | — | — | US | disclosed |
| EP-2683694-A1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | Suzhou Kintor Pharmaceuticals,inc. (CN) | 2014-01-15 | — | — | EP | disclosed |
| WO-2012119559-A1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | SUZHOU KINTOR PHARMACEUTICALS,INC. (CN) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012119559-A1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | SUZHOU KINTOR PHARMACEUTICALS,INC. (CN) | 2012-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140066425-A1 | ANDROGEN RECEPTOR ANTAGONISTS AND USES THEREOF | AR, SHBG, NR5A1 | ADORA2A 761/4885TRPM5 1376/4885AR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.