Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 8/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1249753 | 1.00 | ATM (0.39) | ATMAGTR2FOLH1 | |
| SCHEMBL1249755 | 1.00 | ATM (0.39) | ATMAGTR2FOLH1 | |
| SCHEMBL3405107 | 0.82 | MMP2 (0.49) | — | |
| SCHEMBL13745872 | 0.82 | MMP2 (0.49) | — | |
| SCHEMBL3440720 | 0.81 | ATM (0.43) | ATMAGTR2 | |
| SCHEMBL19064872 | 0.81 | ATM (0.43) | ATMAGTR2 | |
| SCHEMBL29253522 | 0.81 | ATM (0.43) | ATMAGTR2 | |
| SCHEMBL6596413 | 0.81 | ATM (0.43) | ATMAGTR2 | |
| SCHEMBL5160994 | 0.81 | ATM (0.43) | ATMAGTR2 | |
| SCHEMBL2770048 | 0.81 | ATM (0.43) | ATMAGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279737-B1 | Heterocyclic compounds that are active as beta lactamase inhibitors | NOVEXEL (FR) | 2012-10-31 | — | — | EP | disclosed |
| EP-2279737-A1 | Heterocyclic compounds that are active as beta lactamase inhibitors | NOVEXEL (FR) | 2011-02-02 | — | — | EP | disclosed |
| EP-1480644-B1 | NOVEL HETEROCYCLIC COMPOUNDS WHICH ARE ACTIVE AS INHIBITORS OF BETA+LACTAMASES | NOVEXEL (FR) | 2010-10-13 | — | — | EP | disclosed |
| EP-1307457-B1 | AZABICYCLIC COMPOUNDS, PREPARATION THEREOF AND USE AS MEDICINES, IN PARTICULAR AS ANTIBACTERIAL AGENTS | AVENTIS PHARMA SA (FR) | 2004-04-07 | — | — | EP | disclosed |