Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.49 |
| ▸ | ANPEP | P15144 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PEPD | P12955 | 2/20 | 0.37 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3405107 | 1.00 | MMP2 (0.49) | MMP2ANPEPALDH1A1PEPDXPNPEP1 | |
| SCHEMBL3013548 | 0.86 | MMP2 (0.47) | MMP2ANPEPALDH1A1PEPDXPNPEP1 | |
| SCHEMBL7447674 | 0.86 | MMP2 (0.47) | MMP2ANPEPALDH1A1PEPDXPNPEP1 | |
| SCHEMBL31556015 | 0.86 | MMP2 (0.47) | MMP2ANPEPALDH1A1PEPDXPNPEP1 | |
| SCHEMBL1249755 | 0.82 | ATM (0.39) | — | |
| SCHEMBL1249753 | 0.82 | ATM (0.39) | — | |
| SCHEMBL1249758 | 0.82 | ATM (0.39) | — | |
| SCHEMBL318353 | 0.82 | MMP2 (0.47) | MMP2ANPEPALDH1A1PEPDPOLB | |
| SCHEMBL30686137 | 0.82 | MMP2 (0.47) | MMP2ANPEPALDH1A1PEPDPOLB | |
| SCHEMBL23632345 | 0.81 | MMP2 (0.43) | MMP2ANPEPALDH1A1PEPDXPNPEP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097578-A1 | OXIM DERIVATIVES AS HSP90 INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-08-06 | — | — | WO | disclosed |