Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL15663241 | 0.81 | DPP4 (0.44) | KMT2AADORA2AHSD17B10 | |
| Formamide SCHEMBL12498254 | 0.75 | SMN1; SMN2 (0.45) | LOXL2MEN1KMT2AMAPTAPP | |
| SCHEMBL28789839 | 0.73 | POLB (0.41) | LOXL2CDK1CCNB1MEN1KMT2A | |
| Formamide SCHEMBL16969080 | 0.73 | APP (0.46) | MAPTAPPGAAADORA3ADORA2A | |
| SCHEMBL6438986 | 0.72 | HTR7 (0.43) | MEN1KMT2APOLBAPPAR | |
| Formamide SCHEMBL19272521 | 0.71 | TAAR1 (0.38) | MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL473270 | 0.71 | PDCD1 (0.50) | KMT2A | |
| Formamide SCHEMBL12497334 | 0.71 | CA12 (0.40) | LOXL2MEN1KMT2AAPPCYP1A2 | |
| SCHEMBL9194437 | 0.71 | DPP4 (0.58) | LOXL2MEN1KMT2APOLBMAPT | |
| SCHEMBL5843026 | 0.71 | POLB (0.45) | LOXL2CDK1CCNB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012119035-A1 | ANTI-AMYLOID COMPOUNDS AND METHODS | TREVENTIS CORPORATION (US) | 2012-09-07 | — | — | WO | disclosed |