Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.75 |
| ▸ | PKM | P14618 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574072 | 0.90 | ALDH1A1 (0.81) | ALDH1A1PKMSMN1; SMN2POLBMEN1 | |
| SCHEMBL5563528 | 0.89 | ALDH1A1 (0.86) | ALDH1A1PKMSMN1; SMN2POLBMEN1 | |
| SCHEMBL29183277 | 0.87 | ALDH1A1 (0.82) | ALDH1A1PKMSMN1; SMN2POLBMEN1 | |
| SCHEMBL5770948 | 0.84 | ALDH1A1 (0.77) | ALDH1A1PKMSMN1; SMN2POLBMEN1 | |
| SCHEMBL31014207 | 0.83 | ALDH1A1 (0.75) | ALDH1A1PKMSMN1; SMN2POLBMEN1 | |
| SCHEMBL6379743 | 0.83 | ALDH1A1 (0.75) | ALDH1A1PKMSMN1; SMN2POLBMEN1 | |
| SCHEMBL6100066 | 0.83 | ALDH1A1 (0.75) | ALDH1A1PKMSMN1; SMN2POLBMEN1 | |
| SCHEMBL15145873 | 0.83 | ALDH1A1 (0.75) | ALDH1A1PKMSMN1; SMN2POLBMEN1 | |
| SCHEMBL26212922 | 0.82 | ALDH1A1 (0.51) | ALDH1A1PKMSMN1; SMN2POLBMEN1 | |
| SCHEMBL7113122 | 0.81 | ALDH1A1 (1.00) | ALDH1A1PKMSMN1; SMN2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012101648-A1 | NOVEL PROCESS FOR THE SYNTHESIS OF ENANTIOMERICALLY PURE 2-METHOXY-5-[(2R)-2-(4-ALKYLPIPERAZIN-L-YL)PROPYL]-BENZENESULFONAMIDE | HAVALDAR FREDDY H | 2012-08-02 | — | — | WO | claimed |
| CN-117209453-A | Preparation and application of levocetirizine hydrochloride intermediate | 迪嘉药业集团股份有限公司 | 2023-12-12 | — | — | CN | disclosed |