SCHEMBL31014207

SCHEMBL31014207

COCCNS(=O)(=O)c1ccc(OC)cc1

nearest known ligand 0.75

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.75
LMNA P02545 3/20 0.75
SMN1; SMN2 Q16637 3/20 0.75
HPGD P15428 2/20 0.75
PKM P14618 2/20 0.75
KDM4E B2RXH2 1/20 0.75
NPC1 O15118 1/20 0.75
MAPT P10636 1/20 0.75
RAB9A P51151 1/20 0.75
ALOX15 P16050 1/20 0.67
HTT P42858 1/20 0.67
POLB P06746 2/20 0.63
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
TSHR P16473 1/20 0.60
USP2 O75604 1/20 0.60
MAPK1 P28482 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5563528 0.89 ALDH1A1 (0.86) ALDH1A1SMN1; SMN2PKMPOLBMEN1
SCHEMBL29183279 0.85 ALDH1A1 (0.69) ALDH1A1LMNASMN1; SMN2HPGDPKM
SCHEMBL12302132 0.84 ALDH1A1 (0.90) ALDH1A1LMNASMN1; SMN2HPGDPKM
SCHEMBL5770948 0.84 ALDH1A1 (0.77) ALDH1A1LMNASMN1; SMN2PKMHTT
SCHEMBL8340327 0.83 ALDH1A1 (0.76) ALDH1A1LMNASMN1; SMN2HPGDPKM
SCHEMBL24762147 0.83 ALDH1A1 (0.75) ALDH1A1LMNASMN1; SMN2HPGDPKM
SCHEMBL6379743 0.83 ALDH1A1 (0.75) ALDH1A1SMN1; SMN2PKMMAPTALOX15
SCHEMBL386724 0.83 ALDH1A1 (0.75) ALDH1A1LMNASMN1; SMN2HPGDPKM
SCHEMBL12499028 0.83 ALDH1A1 (0.75) ALDH1A1SMN1; SMN2PKMPOLBMEN1
SCHEMBL3126117 0.83 ALDH1A1 (0.75) ALDH1A1LMNASMN1; SMN2HPGDPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118439980-B Synthesis method of alpha-cyano sulfonamide derivative 浙江工业大学 2025-04-08 CN disclosed
CN-118439980-A Synthesis method of alpha-cyano sulfonamide derivative 浙江工业大学 2024-08-06 CN disclosed