Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | REN | P00797 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24322939 | 0.87 | REN (0.57) | LMNARENRECQLHPGDSMC4R | |
| SCHEMBL6632231 | 0.85 | LMNA (0.70) | LMNARENRECQLTSHRKMT2A | |
| SCHEMBL28695962 | 0.84 | LMNA (0.86) | LMNARENRECQLHPGDSTSHR | |
| SCHEMBL20674229 | 0.83 | LMNA (0.73) | LMNARENRECQLHPGDS | |
| SCHEMBL1573549 | 0.80 | RPS6KA5 (0.45) | LMNARENRECQLMC4R | |
| SCHEMBL5633855 | 0.76 | LMNA (0.51) | LMNARENHPGDSTSHRKMT2A | |
| SCHEMBL27284179 | 0.76 | LMNA (0.71) | LMNARECQLKMT2AALDH1A1HPGD | |
| SCHEMBL27284187 | 0.76 | LMNA (0.71) | LMNARECQLKMT2AALDH1A1HPGD | |
| SCHEMBL14814962 | 0.75 | LMNA (0.50) | LMNARENRECQLKMT2AMEN1 | |
| SCHEMBL27287116 | 0.74 | LMNA (0.69) | LMNARECQLKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012101654-A2 | NOVEL TRIAZINE COMPOUNDS | SPHAERA PHARMA PVT. LTD (IN) | 2012-08-02 | — | — | WO | disclosed |