SCHEMBL12499604

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12499540	0.90	TACR1 (0.40)	TACR1ALDH1A1SMN1; SMN2LMNATSHR
	SCHEMBL12687173	0.88	TACR1 (0.38)	TACR1ALDH1A1KDM4ESMN1; SMN2LMNA
	SCHEMBL12498676	0.85	TACR1 (0.40)	TACR1ALDH1A1TP53KDM4ESMN1; SMN2
	SCHEMBL12499336	0.84	TACR1 (0.38)	TACR1ALDH1A1TP53KDM4ESMN1; SMN2
	SCHEMBL12499632	0.84	TACR1 (0.40)	TACR1ALDH1A1TP53SMN1; SMN2LMNA
	SCHEMBL12498474	0.82	TACR1 (0.38)	TACR1TP53POLBMEN1KMT2A
	SCHEMBL12499077	0.82	TACR1 (0.38)	TACR1TP53POLBMEN1KMT2A
	SCHEMBL15346442	0.80	TACR1 (0.38)	TACR1LMNAPOLBCRHR1MAPT
	SCHEMBL12498745	0.78	TACR1 (0.40)	TACR1CRHR1
	SCHEMBL12499967	0.77	TACR1 (0.41)	TACR1ALDH1A1KDM4ELMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.