Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.61 |
| ▸ | RORC | P51449 | 5/20 | 0.60 |
| ▸ | OSBP | P22059 | 4/20 | 0.60 |
| ▸ | USP2 | O75604 | 2/20 | 0.60 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.60 |
| ▸ | OSBP2 | Q969R2 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.55 |
| ▸ | POLA1 | P09884 | 1/20 | 0.55 |
| ▸ | DHCR24 | Q15392 | 1/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.52 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27526586 | 1.00 | CYP19A1 (0.61) | CYP19A1RORCOSBPUSP2CYP46A1 | |
| SCHEMBL2631976 | 0.88 | USP2 (0.74) | CYP19A1RORCOSBPUSP2CYP46A1 | |
| SCHEMBL18409785 | 0.88 | USP2 (0.74) | CYP19A1RORCOSBPUSP2CYP46A1 | |
| SCHEMBL932451 | 0.88 | USP2 (0.74) | CYP19A1RORCOSBPUSP2CYP46A1 | |
| SCHEMBL24264118 | 0.88 | USP2 (0.74) | CYP19A1RORCOSBPUSP2CYP46A1 | |
| SCHEMBL24927685 | 0.88 | USP2 (0.74) | CYP19A1RORCOSBPUSP2CYP46A1 | |
| SCHEMBL11977916 | 0.88 | USP2 (0.74) | CYP19A1RORCOSBPUSP2CYP46A1 | |
| SCHEMBL14558147 | 0.88 | USP2 (0.74) | CYP19A1RORCOSBPUSP2CYP46A1 | |
| SCHEMBL7601730 | 0.88 | USP2 (0.74) | CYP19A1RORCOSBPUSP2CYP46A1 | |
| SCHEMBL14052247 | 0.88 | USP2 (0.74) | CYP19A1RORCOSBPUSP2CYP46A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9234885-B2 | Methods and assays for treating filoviridae infections | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2016-01-12 | — | — | US | disclosed |
| US-20140018338-A1 | METHODS AND ASSAYS FOR TREATING FILOVIRIDAE INFECTIONS | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2014-01-16 | — | — | US | disclosed |
| WO-2012103081-A1 | METHODS AND ASSAYS FOR TREATING FILOVIRIDAE INFECTIONS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2012-08-02 | — | — | WO | disclosed |
| CN-1242017-A | Meiosis regulating compounds | NOVO NORDISK AS (DK) | 2000-01-19 | — | — | CN | disclosed |