Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEH1 | O60930 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 2/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8267930 | 0.88 | RNASEH1 (0.56) | RNASEH1MEN1KMT2ATNKSTNKS2 | |
| SCHEMBL13218149 | 0.83 | RNASEH1 (0.40) | RNASEH1MEN1KMT2ATNKSTNKS2 | |
| SCHEMBL13302558 | 0.81 | RNASEH1 (0.53) | RNASEH1MEN1KMT2ATNKSTNKS2 | |
| SCHEMBL12777995 | 0.80 | RNASEH1 (0.49) | RNASEH1MEN1KMT2ATNKSTNKS2 | |
| SCHEMBL12777996 | 0.76 | CYP1A2 (0.39) | MEN1KMT2ATNKSTNKS2ALDH1A1 | |
| SCHEMBL1150858 | 0.72 | MEN1 (0.45) | RNASEH1MEN1KMT2AERCC1FEN1 | |
| SCHEMBL8266635 | 0.71 | KCNE1 (0.43) | RNASEH1MEN1KMT2AALDH1A1ERCC1 | |
| SCHEMBL13218179 | 0.70 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2ATMCTSS | |
| SCHEMBL18196234 | 0.70 | MEN1 (0.43) | RNASEH1MEN1KMT2ASMN1; SMN2ATM | |
| SCHEMBL13218239 | 0.70 | KMT2A (0.41) | RNASEH1MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012103105-A1 | PROCESSES FOR PREPARING RALTEGRAVIR AND INTERMEDIATES IN THE PROCESSES | ASSIA CHEMICAL INDUSTRIES LTD. (IL) | 2012-08-02 | — | — | WO | disclosed |