SCHEMBL12503528

SCHEMBL12503528

COCC[Si](C)(C)C.F[B-](F)(F)F.F[B-](F)(F)F.F[B-](F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28936008 0.97
SCHEMBL8009 0.88
Hydrochloric Acid SCHEMBL866240 0.85
Ammonia Solution, Strong SCHEMBL16110998 0.85
SCHEMBL3143889 0.75 TSHR (0.33)
SCHEMBL30621784 0.72 CA2 (0.34)
SCHEMBL1041150 0.72 CA2 (0.34)
SCHEMBL7081970 0.72
SCHEMBL6971201 0.71
SCHEMBL19546337 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012169909-A1 TRIAMINOCYCLOPROPENIUM SALTS CURNOW OWEN JOHN (NZ) 2012-12-13 WO claimed
EP-2593107-A1 TYROSINE KINASE INHIBITORS Merck Sharp & Dohme Corp. (US) 2013-05-22 EP disclosed
US-20130116231-A1 TYROSINE KINASE INHIBITORS MERCK SHARP & DOHME CORP. 2013-05-09 US disclosed
WO-2012169909-A1 TRIAMINOCYCLOPROPENIUM SALTS CURNOW OWEN JOHN (NZ) 2012-12-13 WO disclosed
WO-2012009194-A1 TYROSINE KINASE INHIBITORS MERCK SHARP & DOHME CORP. (US) 2012-01-19 WO disclosed