SCHEMBL12504151

SCHEMBL12504151

O=C(CCC(C1CCCCC1)(C1CCCCC1)C1CCCCC1)O[SiH3]

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
SSTR4 P31391 1/20 0.32
NAAA Q02083 1/20 0.31
EPHX2 P34913 1/20 0.31
HPGD P15428 1/20 0.30
MIF P14174 1/20 0.30
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12504250 0.98 LMNA (0.30) LMNA
SCHEMBL12504392 0.89 NAAA (0.36) LMNASSTR4NAAAEPHX2
SCHEMBL12504180 0.87 NAAA (0.34) LMNANAAAEPHX2
SCHEMBL12504503 0.82 SSTR4 (0.36) LMNASSTR4NAAAEPHX2EPHX1
SCHEMBL12504240 0.82 SSTR4 (0.36) LMNASSTR4NAAAEPHX2EPHX1
SCHEMBL12504362 0.80 SSTR4 (0.34) LMNASSTR4NAAAEPHX2
SCHEMBL12504485 0.80 NAAA (0.34) SSTR4NAAAEPHX2
SCHEMBL12504115 0.80 NAAA (0.34) SSTR4NAAAEPHX2EPHX1
SCHEMBL12504603 0.80 NAAA (0.34) SSTR4NAAAEPHX2EPHX1
SCHEMBL12504404 0.78 NAAA (0.36) SSTR4NAAAEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2658877-B1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORP (JP) 2023-04-12 EP disclosed
US-9546237-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2017-01-17 US disclosed
US-9499683-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2016-11-22 US disclosed
US-20140031471-A1 Stabilization Of Polymers That Contain A Hydrolyzable Functionality BRIDGESTONE CORPORATION (JP) 2014-01-30 US disclosed
US-20130331520-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2013-12-12 US disclosed
EP-2658877-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY Bridgestone Corporation (JP) 2013-11-06 EP disclosed
WO-2012092626-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2012-07-05 WO disclosed