SCHEMBL12504166

SCHEMBL12504166

CCCCC([SiH3])C(=O)OOC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 0.42
CA1 P00915 4/20 0.42
MAPK1 P28482 1/20 0.37
CTSK P43235 4/20 0.37
TSHR P16473 2/20 0.34
CYP3A4 P08684 1/20 0.34
ATM Q13315 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CTSS P25774 1/20 0.33
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
ZDHHC7 Q9NXF8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12504390 0.85 CTSK (0.42) CA2CA1MAPK1CTSKTSHR
SCHEMBL210333 0.80 CA2 (0.61) CA2CA1MAPK1CTSKTSHR
SCHEMBL21925211 0.79 CA2 (0.50) CA2CA1MAPK1SLC1A2SLC1A1
SCHEMBL12504496 0.76 CA2 (0.39) CA2CA1MAPK1TSHRCYP3A4
SCHEMBL28870964 0.76 CA1 (0.41) CA2CA1SLC1A2SLC1A1ZDHHC7
SCHEMBL12504567 0.75 CA1 (0.31) CA2CA1
Decane SCHEMBL12471611 0.74 MAPT (0.41) CA2CA1MAPK1ZDHHC7
SCHEMBL12504528 0.74 CTSK (0.39) CA2CA1MAPK1CTSKTSHR
SCHEMBL23277366 0.72 USP2 (0.41) CA2CA1ZDHHC7
Hexanoate SCHEMBL31031296 0.71 CA2 (0.50) CA2CA1MAPK1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2658877-B1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORP (JP) 2023-04-12 EP disclosed
US-9546237-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2017-01-17 US disclosed
US-9499683-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2016-11-22 US disclosed
US-20140031471-A1 Stabilization Of Polymers That Contain A Hydrolyzable Functionality BRIDGESTONE CORPORATION (JP) 2014-01-30 US disclosed
US-20130331520-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2013-12-12 US disclosed
EP-2658877-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY Bridgestone Corporation (JP) 2013-11-06 EP disclosed
WO-2012092626-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2012-07-05 WO disclosed