SCHEMBL12504243

SCHEMBL12504243

CC(C)C(C)([SiH3])C(=O)OC1CCCCC1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.45
EPHX1 P07099 2/20 0.40
NAAA Q02083 2/20 0.37
HTT P42858 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
CYP2C19 P33261 2/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
CHRM3 P20309 4/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12504364 0.98 CYP19A1 (0.43) CYP19A1EPHX1NAAAHTTSMN1; SMN2
SCHEMBL12504505 0.85 CYP19A1 (0.42) CYP19A1EPHX1NAAAHTTSMN1; SMN2
SCHEMBL12504486 0.83 CYP19A1 (0.40) CYP19A1EPHX1NAAAHTTSMN1; SMN2
SCHEMBL11991229 0.81 CYP19A1 (0.47) CYP19A1EPHX1NAAAHTTSMN1; SMN2
SCHEMBL12504114 0.81 EPHX1 (0.40) CYP19A1EPHX1NAAAHTTSMN1; SMN2
SCHEMBL12504604 0.81 NAAA (0.41) CYP19A1EPHX1NAAAHTTSMN1; SMN2
SCHEMBL12504471 0.79 NAAA (0.40) CYP19A1EPHX1NAAAHTTSMN1; SMN2
SCHEMBL24134017 0.79 CYP19A1 (0.45) CYP19A1EPHX1NAAAHTTSMN1; SMN2
SCHEMBL13953762 0.79 CYP19A1 (0.45) CYP19A1EPHX1NAAAHTTSMN1; SMN2
SCHEMBL12504105 0.78 EPHX1 (0.41) CYP19A1EPHX1NAAAHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2658877-B1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORP (JP) 2023-04-12 EP disclosed
US-9546237-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2017-01-17 US disclosed
US-9499683-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2016-11-22 US disclosed
US-20140031471-A1 Stabilization Of Polymers That Contain A Hydrolyzable Functionality BRIDGESTONE CORPORATION (JP) 2014-01-30 US disclosed
US-20130331520-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2013-12-12 US disclosed
EP-2658877-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY Bridgestone Corporation (JP) 2013-11-06 EP disclosed
WO-2012092626-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2012-07-05 WO disclosed