SCHEMBL12504604

SCHEMBL12504604

CCCC(C)C(C)([SiH3])C(=O)OC1CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.41
EPHX1 P07099 2/20 0.41
CYP19A1 P11511 2/20 0.40
HTT P42858 3/20 0.34
CYP2C19 P33261 2/20 0.33
SMN1; SMN2 Q16637 3/20 0.32
ALDH1A1 P00352 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32
ADRA1A P35348 1/20 0.32
CHRNA4 P43681 1/20 0.32
HTR3A P46098 1/20 0.32
KCNH2 Q12809 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12504471 0.98 NAAA (0.40) NAAAEPHX1CYP19A1HTTCYP2C19
SCHEMBL12504114 0.86 EPHX1 (0.40) NAAAEPHX1CYP19A1HTTCYP2C19
SCHEMBL12504248 0.83 NAAA (0.39) NAAAEPHX1CYP19A1HTTCYP2C19
SCHEMBL12504171 0.83 NAAA (0.39) NAAAEPHX1CYP19A1HTTCYP2C19
SCHEMBL12504296 0.81 NAAA (0.38) NAAAEPHX1CYP19A1HTTSMN1; SMN2
SCHEMBL12504595 0.81 NAAA (0.38) NAAAEPHX1CYP19A1HTTSMN1; SMN2
SCHEMBL12504243 0.81 CYP19A1 (0.45) NAAAEPHX1CYP19A1HTTCYP2C19
SCHEMBL12504364 0.79 CYP19A1 (0.43) NAAAEPHX1CYP19A1HTTCYP2C19
SCHEMBL12504505 0.77 CYP19A1 (0.42) NAAAEPHX1CYP19A1HTTCYP2C19
SCHEMBL12504105 0.77 EPHX1 (0.41) NAAAEPHX1CYP19A1HTTCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2658877-B1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORP (JP) 2023-04-12 EP disclosed
US-9546237-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2017-01-17 US disclosed
US-9499683-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2016-11-22 US disclosed
US-20140031471-A1 Stabilization Of Polymers That Contain A Hydrolyzable Functionality BRIDGESTONE CORPORATION (JP) 2014-01-30 US disclosed
US-20130331520-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2013-12-12 US disclosed
EP-2658877-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY Bridgestone Corporation (JP) 2013-11-06 EP disclosed
WO-2012092626-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2012-07-05 WO disclosed