SCHEMBL12504369

SCHEMBL12504369

CCCCCC(=O)O[Si](CCCCC)(OC)OC

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.46
LMNA P02545 4/20 0.43
PAM P19021 2/20 0.42
MAPT P10636 2/20 0.41
MAPK1 P28482 1/20 0.41
CES2 O00748 4/20 0.40
CES1 P23141 4/20 0.40
TSHR P16473 1/20 0.40
AKR1B1 P15121 1/20 0.39
DNM1 Q05193 1/20 0.39
POLB P06746 1/20 0.39
POLA1 P09884 1/20 0.39
ALDH1A1 P00352 1/20 0.39
NAAA Q02083 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12504320 0.91 LMNA (0.43) DGKALMNAPAMCES2CES1
SCHEMBL12504184 0.91 DGKA (0.38) DGKALMNAPAMMAPTMAPK1
SCHEMBL28413444 0.87 DGKA (0.42) DGKALMNAPAMMAPTMAPK1
SCHEMBL28418415 0.87 DGKA (0.42) DGKALMNAPAMMAPTMAPK1
SCHEMBL28423769 0.87 DGKA (0.42) DGKALMNAPAMMAPTMAPK1
SCHEMBL28424194 0.87 DGKA (0.42) DGKALMNAPAMMAPTMAPK1
SCHEMBL28419697 0.87 DGKA (0.42) DGKALMNAPAMMAPTMAPK1
SCHEMBL28418523 0.87 DGKA (0.42) DGKALMNAPAMMAPTMAPK1
SCHEMBL28418427 0.87 DGKA (0.42) DGKALMNAPAMMAPTMAPK1
SCHEMBL28423579 0.87 DGKA (0.42) DGKALMNAPAMMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2658877-B1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORP (JP) 2023-04-12 EP disclosed
US-9546237-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2017-01-17 US disclosed
US-9499683-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2016-11-22 US disclosed
US-20140031471-A1 Stabilization Of Polymers That Contain A Hydrolyzable Functionality BRIDGESTONE CORPORATION (JP) 2014-01-30 US disclosed
US-20130331520-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2013-12-12 US disclosed
EP-2658877-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY Bridgestone Corporation (JP) 2013-11-06 EP disclosed
WO-2012092626-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2012-07-05 WO disclosed