⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600094 | 0.72 | — | — | |
| SCHEMBL1250482 | 0.69 | — | — | |
| SCHEMBL3817904 | 0.69 | — | — | |
| SCHEMBL1736653 | 0.69 | — | — | |
| SCHEMBL3066035 | 0.68 | — | — | |
| SCHEMBL2438668 | 0.68 | — | — | |
| SCHEMBL4729327 | 0.67 | — | — | |
| SCHEMBL6219603 | 0.66 | — | — | |
| SCHEMBL5898964 | 0.66 | — | — | |
| SCHEMBL10446539 | 0.64 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370434-A1 | CORYDALINE DERIVATIVES USEFUL FOR REDUCING LIPID LEVELS | CVI Pharmaceuticals Limited (KY) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010075469-A1 | CORYDALINE DERIVATIVES USEFUL FOR REDUCING LIPID LEVELS | CVI PHARMACEUTICALS LIMITED (KY) | 2010-07-01 | — | — | WO | disclosed |