⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600094 | 0.72 | — | — | |
| SCHEMBL2465696 | 0.69 | — | — | |
| SCHEMBL1250482 | 0.69 | — | — | |
| SCHEMBL3817904 | 0.69 | — | — | |
| SCHEMBL3066035 | 0.68 | — | — | |
| SCHEMBL4729327 | 0.67 | — | — | |
| SCHEMBL9770023 | 0.67 | KDM4E (0.35) | — | |
| SCHEMBL6219603 | 0.66 | — | — | |
| SCHEMBL5898964 | 0.66 | — | — | |
| SCHEMBL10446539 | 0.64 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814334-A1 | 4-SUBSTITUTED PHENYL-1,3,5-TRIAZINE DERIVATIVES AS MODULATORS OF TRK RECEPTORS | Alzecure Pharma AB (SE) | 2021-05-05 | — | — | EP | claimed |
| US-20210145824-A1 | MODULATORS OF CELLULAR ADHESION | NOVARTIS PHARMACEUTICALS CORPORATION (US) | 2021-05-20 | — | — | US | disclosed |
| US-8846661-B2 | Diazahomoadamantane derivatives and methods of use thereof | ABBVIE INC. (US) | 2014-09-30 | — | — | US | disclosed |
| EP-2443122-B1 | DIAZAHOMOADAMANTANE DERIVATIVES AND METHODS OF USE THEREOF | ABBVIE INC (US) | 2014-03-05 | — | — | EP | disclosed |
| EP-2443122-A1 | DIAZAHOMOADAMANTANE DERIVATIVES AND METHODS OF USE THEREOF | Abbott Laboratories (US) | 2012-04-25 | — | — | EP | disclosed |
| US-8084615-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2011-12-27 | — | — | US | disclosed |
| EP-1838693-B1 | PYRAZOLE DERIVATIVES AS PESTICIDES | MERIAL LTD (US) | 2011-11-16 | — | — | EP | disclosed |
| US-20110265005-A1 | METHOD, SYSTEM AND APPARATUS FOR MANAGING MESSAGE ATTACHMENTS | RESEARCH IN MOTION LIMITED (CA) | 2011-10-27 | — | — | US | disclosed |
| US-20100324027-A1 | DIAZAHOMOADAMANTANE DERIVATIVES AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2010-12-23 | — | — | US | disclosed |
| WO-2010145208-A1 | DIAZAHOMOADAMANTANE DERIVATIVES AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2010-12-23 | — | — | WO | disclosed |
| US-20090247506-A1 | Antibacterial agents | CHIRON CORPORATION | 2009-10-01 | — | — | US | disclosed |
| US-20090163496-A1 | ANTIBACTERIAL AGENTS | UNIVERSITY OF WASHINGTON (US) | 2009-06-25 | — | — | US | disclosed |
| US-7148228-B2 | Pyrazolopyrimidines and related analogs as HSP90-inhibitors | CONFORMA THERAPEUTICS CORPORATION (US) | 2006-12-12 | — | — | US | disclosed |
| EP-1140900-A4 | PYRAZOLE COMPOUNDS AND USES THEREOF | PPD DISCOVERY INC (US) | 2002-04-10 | — | — | EP | disclosed |
| EP-1140900-A2 | PYRAZOLE COMPOUNDS AND USES THEREOF | PPD DISCOVERY, INC. (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039083-A2 | PYRAZOLE COMPOUNDS AND USES THEREOF | PPD DISCOVERY, INC. (US) | 2000-07-06 | — | — | WO | disclosed |