Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 9/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | CDC7 | O00311 | 2/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5743995 | 0.89 | TRPM8 (0.45) | CDC7DBF4TRPM8MAPTKDM4E | |
| SCHEMBL1250874 | 0.83 | CNR1 (0.57) | CNR1CNR2CDC7DBF4CCNE1 | |
| SCHEMBL5038508 | 0.81 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL1250865 | 0.80 | CDC7 (0.58) | CNR1CNR2CDC7DBF4TRPM8 | |
| SCHEMBL4430376 | 0.77 | CNR1 (0.65) | CNR1CNR2CDC7DBF4CCNE1 | |
| SCHEMBL1251360 | 0.77 | CNR1 (0.49) | CNR1CNR2CDC7DBF4CCNE1 | |
| SCHEMBL5036951 | 0.75 | CNR1 (0.67) | CNR1CNR2LMNANPSR1MAPT | |
| SCHEMBL5038585 | 0.73 | CNR1 (0.64) | CNR1CNR2CDC7DBF4CCNE1 | |
| SCHEMBL5034224 | 0.73 | CNR1 (0.57) | CNR1CNR2CDC7DBF4CCNE1 | |
| SCHEMBL6189633 | 0.73 | CDC7 (0.52) | CNR1CNR2CDC7DBF4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664005-B1 | THIAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | ABBOTT HEALTHCARE PRODUCTS BV (NL) | 2011-02-09 | — | — | EP | disclosed |
| EP-1664005-A1 | THIAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | Solvay Pharmaceuticals B.V. (NL) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005028456-A1 | THIAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | SOLVAY PHARMACEUTICALS B.V. (NL) | 2005-03-31 | — | — | WO | disclosed |
| US-20050065189-A1 | Thiazole derivatives as cannabinoid receptor modulators | SOLVAY PHARMACEUTICALS B.V. | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065189-A1 | Thiazole derivatives as cannabinoid receptor modulators | CNR1, CNR2, NPY1R | CNR1 1/4885CNR2 2/4885CDC7 3903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.