Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.80 |
| ▸ | KRAS | P01116 | 10/20 | 0.72 |
| ▸ | NT5E | P21589 | 1/20 | 0.68 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.67 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.63 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.62 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.62 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.62 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21742688 | 0.99 | TGM2 (0.81) | TGM2KRASNT5EFUT5P2RX3 | |
| SCHEMBL24409582 | 0.94 | TGM2 (0.75) | TGM2KRASNT5EFUT5P2RX3 | |
| SCHEMBL13419012 | 0.94 | TGM2 (0.75) | TGM2KRASNT5EFUT5P2RX3 | |
| SCHEMBL21742683 | 0.94 | NT5E (0.74) | TGM2KRASNT5EFUT5 | |
| SCHEMBL851357 | 0.91 | TGM2 (0.85) | TGM2KRASNT5EFUT5P2RX3 | |
| SCHEMBL18769114 | 0.91 | TGM2 (0.85) | TGM2KRASNT5EFUT5P2RX3 | |
| SCHEMBL21067722 | 0.91 | TGM2 (0.85) | TGM2KRASNT5EFUT5P2RX3 | |
| SCHEMBL29429843 | 0.91 | TGM2 (0.85) | TGM2KRASNT5EFUT5P2RX3 | |
| SCHEMBL24409555 | 0.90 | TGM2 (0.83) | TGM2KRASNT5EFUT5P2RX3 | |
| SCHEMBL21742748 | 0.90 | TGM2 (0.78) | TGM2KRASNT5EFUT5P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110177527-A1 | METHODS AND COMPOUNDS FOR TESTING BINDING OF A LIGAND TO A G PROTEIN-COUPLED RECEPTOR | GE HEALTHCARE UK LIMITED (GB) | 2011-07-21 | — | — | US | disclosed |
| US-7674584-B2 | Method for measuring binding of a test compound to a G-protein coupled receptor | GE HEALTHCARE UK LIMITED (GB) | 2010-03-09 | — | — | US | disclosed |
| US-7674584-B2 | Method for measuring binding of a test compound to a G-protein coupled receptor | GE HEALTHCARE UK LIMITED (GB) | 2010-03-09 | — | — | US | disclosed |
| US-7445902-B2 | Fluorescent nucleotide analogues | GE HEALTHCARE UK LIMITED (GB) | 2008-11-04 | — | — | US | disclosed |
| US-7445902-B2 | Fluorescent nucleotide analogues | GE HEALTHCARE UK LIMITED (GB) | 2008-11-04 | — | — | US | disclosed |
| US-20070287162-A1 | Fluorescent Nucleotide Analogues | GE HEALTHCARE UK LIMITED (GB) | 2007-12-13 | — | — | US | disclosed |
| US-20070287162-A1 | Fluorescent Nucleotide Analogues | GE HEALTHCARE UK LIMITED (GB) | 2007-12-13 | — | — | US | disclosed |
| US-20070218520-A1 | Method for Measuring Binding of a Test Compound to a G-Protein Coupled Receptor | GE HEALTHCARE UK LIMITED (GB) | 2007-09-20 | — | — | US | disclosed |
| US-20070218520-A1 | Method for Measuring Binding of a Test Compound to a G-Protein Coupled Receptor | GE HEALTHCARE UK LIMITED (GB) | 2007-09-20 | — | — | US | disclosed |