Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 3/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 3/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14542772 | 1.00 | SLC1A3 (0.43) | SLC1A3SLC1A2SLC1A1LTA4HMME | |
| SCHEMBL14472554 | 0.91 | MAPT (0.44) | SLC1A3SLC1A2SLC1A1CTSLCTSS | |
| SCHEMBL17366090 | 0.87 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| SCHEMBL14542658 | 0.84 | ADAMTS4 (0.50) | CTSLCTSSCTSKALDH1A1HTT | |
| SCHEMBL6830160 | 0.83 | SLC1A3 (0.49) | SLC1A3SLC1A2SLC1A1LTA4HMME | |
| SCHEMBL16821240 | 0.83 | SLC1A3 (0.49) | SLC1A3SLC1A2SLC1A1LTA4HMME | |
| SCHEMBL6092218 | 0.83 | LTA4H (0.54) | LTA4HMMEITGB3ITGA2BACE | |
| SCHEMBL14542796 | 0.82 | POLB (0.47) | SLC1A3SLC1A2SLC1A1CTSLCTSS | |
| SCHEMBL14542585 | 0.80 | SLC1A3 (0.46) | SLC1A3SLC1A2SLC1A1ITGB3ITGA2B | |
| SCHEMBL29613221 | 0.77 | SLC1A3 (0.57) | SLC1A3SLC1A2SLC1A1LTA4HMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1808440-B1 | Non-covalent inhibitors of urokinase and blood vessel formation | WILEX AG (DE) | 2011-07-27 | — | — | EP | disclosed |
| EP-1808440-A1 | Non-covalent inhibitors of urokinase and blood vessel formation | Wilex AG (DE) | 2007-07-18 | — | — | EP | disclosed |