Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS6 | Q8IU80 | 9/20 | 0.48 |
| ▸ | F7 | P08709 | 6/20 | 0.48 |
| ▸ | F2 | P00734 | 11/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | F3 | P13726 | 2/20 | 0.42 |
| ▸ | PROC | P04070 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12514168 | 0.86 | ITGB3 (0.48) | TMPRSS6F7F2ST14F10 | |
| SCHEMBL8290770 | 0.86 | F2 (0.53) | TMPRSS6F7F2ST14F10 | |
| SCHEMBL8346530 | 0.84 | F2 (0.57) | TMPRSS6F2F10ADRA1B | |
| SCHEMBL8345186 | 0.84 | F2 (0.51) | TMPRSS6F2F10PROCADRA1B | |
| SCHEMBL8345195 | 0.84 | F2 (0.49) | TMPRSS6F7F2ST14F10 | |
| SCHEMBL24322931 | 0.80 | ST14 (0.52) | TMPRSS6F7F2ST14F10 | |
| SCHEMBL8344650 | 0.80 | F2 (0.56) | TMPRSS6F2F10PROCADRA1B | |
| Hydrochloric Acid SCHEMBL6366354 | 0.78 | F7 (0.44) | TMPRSS6F7F2ST14F10 | |
| SCHEMBL7118946 | 0.77 | MEN1 (0.53) | F7F2F10PROCADRA1B | |
| Hydrochloric Acid SCHEMBL6366518 | 0.77 | F2 (0.54) | F7F2F10PROCADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1808440-B1 | Non-covalent inhibitors of urokinase and blood vessel formation | WILEX AG (DE) | 2011-07-27 | — | — | EP | disclosed |