Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.48 |
| ▸ | TMPRSS6 | Q8IU80 | 4/20 | 0.44 |
| ▸ | F7 | P08709 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 7/20 | 0.42 |
| ▸ | F10 | P00742 | 4/20 | 0.42 |
| ▸ | TMPRSS11D | O60235 | 3/20 | 0.42 |
| ▸ | PLG | P00747 | 3/20 | 0.42 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | PROC | P04070 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12514173 | 0.86 | TMPRSS6 (0.48) | TMPRSS6F7F2F10ST14 | |
| SCHEMBL12514664 | 0.85 | F2 (0.48) | ITGB3ITGA2BF7F2 | |
| SCHEMBL8345186 | 0.83 | F2 (0.51) | TMPRSS6F2F10TMPRSS11DPLG | |
| SCHEMBL8346530 | 0.83 | F2 (0.57) | TMPRSS6F2F10TMPRSS11DPLG | |
| SCHEMBL8345195 | 0.83 | F2 (0.49) | TMPRSS6F7F2F10TMPRSS11D | |
| SCHEMBL12513998 | 0.83 | F10 (0.40) | ITGB3ITGA2BF2F10PLG | |
| SCHEMBL8344650 | 0.79 | F2 (0.56) | TMPRSS6F2F10TMPRSS11DPLG | |
| SCHEMBL5502070 | 0.78 | ITGB3 (0.41) | ITGB3ITGA2BF7F2F10 | |
| Hydrochloric Acid SCHEMBL6544381 | 0.77 | ITGB3 (0.40) | ITGB3ITGA2BF7F2F10 | |
| SCHEMBL12514559 | 0.77 | F2 (0.54) | F2F10TMPRSS11DPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1808440-B1 | Non-covalent inhibitors of urokinase and blood vessel formation | WILEX AG (DE) | 2011-07-27 | — | — | EP | disclosed |