Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.48 |
| ▸ | MASP2 | O00187 | 6/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12514600 | 0.89 | F7 (0.42) | F2MASP2ITGB3ITGA2BF7 | |
| SCHEMBL12514663 | 0.86 | ITGB3 (0.44) | F2MASP2ITGB3ITGA2BF7 | |
| SCHEMBL12514168 | 0.85 | ITGB3 (0.48) | F2ITGB3ITGA2BF7 | |
| SCHEMBL12514672 | 0.79 | F2 (0.54) | F2MASP2 | |
| SCHEMBL12514587 | 0.77 | PLG (0.36) | F2ITGB3ITGA2B | |
| SCHEMBL12514177 | 0.77 | F2 (0.58) | F2MASP2F7 | |
| SCHEMBL12514178 | 0.76 | F2 (0.56) | F2F7 | |
| SCHEMBL12514559 | 0.76 | F2 (0.54) | F2MASP2 | |
| SCHEMBL12514336 | 0.75 | SIRT2 (0.42) | ITGB3ITGA2B | |
| SCHEMBL12847292 | 0.75 | F2 (0.58) | F2F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1808440-B1 | Non-covalent inhibitors of urokinase and blood vessel formation | WILEX AG (DE) | 2011-07-27 | — | — | EP | disclosed |
| EP-1808440-A1 | Non-covalent inhibitors of urokinase and blood vessel formation | Wilex AG (DE) | 2007-07-18 | — | — | EP | disclosed |