Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 12/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15489089 | 0.88 | TYMP (0.53) | TYMPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL21431111 | 0.88 | TYMP (0.53) | TYMPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL12067762 | 0.85 | BCHE (0.49) | TYMPALDH1A1MAPK1BCHE | |
| SCHEMBL29673058 | 0.85 | TYMP (0.87) | TYMPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL18486353 | 0.85 | TYMP (0.87) | TYMPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL1697166 | 0.84 | HPGD (0.50) | TYMPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL20028665 | 0.83 | TYMP (0.49) | TYMPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL15488819 | 0.83 | TYMP (0.51) | TYMPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL22458596 | 0.83 | TYMP (0.56) | TYMPCYP1A2BCHE | |
| SCHEMBL23641899 | 0.83 | TYMP (0.60) | TYMPALDH1A1LMNAALBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3658565-B1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2022-11-09 | — | — | EP | disclosed |
| WO-2019023459-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-01-31 | — | — | WO | disclosed |
| WO-2011084345-A1 | A METHOD FOR RAPIDLY EVALUATING PERFORMANCE OF SHORT INTERFERING RNA WITH NOVEL CHEMICAL MODIFICATIONS | MERCK SHARP & DOHME CORP. (US) | 2011-07-14 | — | — | WO | disclosed |