Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 12/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.35 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12515629 | 0.88 | TYMP (0.68) | TYMPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL20028665 | 0.86 | TYMP (0.49) | TYMPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL22879117 | 0.85 | TYMP (0.59) | TYMPPAX8 | |
| SCHEMBL15489089 | 0.85 | TYMP (0.53) | TYMPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL22643618 | 0.82 | TYMP (0.46) | TYMPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL19505895 | 0.82 | TYMP (0.49) | TYMPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL1697166 | 0.82 | HPGD (0.50) | TYMPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL21431259 | 0.81 | TYMP (0.78) | TYMPPAX8 | |
| SCHEMBL22879159 | 0.81 | TYMP (0.78) | TYMPPAX8 | |
| SCHEMBL15488819 | 0.81 | TYMP (0.51) | TYMPALDH1A1LMNAALBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019185477-A1 | CYCLIC DINUCLEOTIDE COMPOUNDS CONTAINING 2-AZA-HYPOXANTHINE OR 6H-PYTAZOLO[1,5-D][1,2,4]TRIAZIN-7-ONE AS STING AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-10-03 | — | — | WO | disclosed |