Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 2/20 | 0.48 |
| ▸ | TYMP | P19971 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HINT1 | P49773 | 2/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15489089 | 0.97 | TYMP (0.53) | HPGDXDHTYMPALDH1A1LMNA | |
| SCHEMBL15488819 | 0.92 | TYMP (0.51) | HPGDXDHTYMPALDH1A1LMNA | |
| SCHEMBL15482429 | 0.84 | TYMP (0.42) | HPGDXDHTYMPALDH1A1LMNA | |
| SCHEMBL15482427 | 0.84 | TYMP (0.42) | HPGDXDHTYMPALDH1A1LMNA | |
| SCHEMBL12515629 | 0.84 | TYMP (0.68) | TYMPALDH1A1LMNAALBMAPK1 | |
| SCHEMBL25057493 | 0.84 | ALDH1A1 (0.52) | HPGDXDHALDH1A1LMNAALB | |
| SCHEMBL18520392 | 0.84 | ALDH1A1 (0.52) | HPGDXDHALDH1A1LMNAALB | |
| SCHEMBL22523989 | 0.84 | ALDH1A1 (0.52) | HPGDXDHALDH1A1LMNAALB | |
| SCHEMBL26794936 | 0.84 | ALDH1A1 (0.52) | HPGDXDHALDH1A1LMNAALB | |
| SCHEMBL19505895 | 0.83 | TYMP (0.49) | HPGDTYMPALDH1A1LMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170305954-A1 | SYNTHESIS OF 2', 3'-DIDEOXYNUCLEOSIDES FOR AUTOMATED DNA SYNTHESIS AND PYROPHOSPHOROLYSIS ACTIVATED POLYMERIZATION | Life Technologies Corporation (US) | 2017-10-26 | — | — | US | disclosed |
| US-9732112-B2 | Synthesis of 2′,3′-dideoxynucleosides for automated DNA synthesis and pyrophosphorolysis activated polymerization | Life Technologies Corporation (US) | 2017-08-15 | — | — | US | disclosed |
| US-20160108079-A1 | Synthesis Of 2',3'-Dideoxynucleosides For Automated DNA Synthesis And Pyrophosphorolysis Activated Polymerization | Life Technologies Corporation | 2016-04-21 | — | — | US | disclosed |
| US-9228227-B2 | Synthesis of 2′, 3′-dideoxynucleosides for automated DNA synthesis and pyrophosphorolysis activated polymerization | Life Technologies Corporation (US) | 2016-01-05 | — | — | US | disclosed |
| EP-2576577-B1 | SYNTHESIS OF 2', 3'-DIDEOXYNUCLEOSIDES FOR AUTOMATED DNA SYNTHESIS AND PYROPHOSPHOROLYSIS ACTIVATED POLYMERIZATION | LIFE TECHNOLOGIES CORP (US) | 2015-03-18 | — | — | EP | disclosed |
| US-20150045547-A1 | Synthesis Of 2' , 3' -Dideoxynucleosides For Automated DNA Synthesis And Pyrophosphorolysis Activated Polymerization | Life Technologies Corporation (US) | 2015-02-12 | — | — | US | disclosed |
| US-8658776-B2 | Synthesis of 2′,3′-dideoxynucleosides for automated DNA synthesis and pyrophosphorolysis activated polymerization | Life Technologies Corporation (US) | 2014-02-25 | — | — | US | disclosed |
| EP-2576577-A2 | SYNTHESIS OF 2', 3'-DIDEOXYNUCLEOSIDES FOR AUTOMATED DNA SYNTHESIS AND PYROPHOSPHOROLYSIS ACTIVATED POLYMERIZATION | Life Technologies Corporation (US) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011150277-A2 | SYNTHESIS OF 2', 3'-DIDEOXYNUCLEOSIDES FOR AUTOMATED DNA SYNTHESIS AND PYROPHOSPHOROLYSIS ACTIVATED POLYMERIZATION | Life Technologies Corporation (US) | 2011-12-01 | — | — | WO | disclosed |
| US-20110294122-A1 | Synthesis of 2', 3'-Dideoxynucleosides for Automated DNA Synthesis and Pyrophosphorolysis Activated Polymerization | Life Technologies Corporation (US) | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305954-A1 | SYNTHESIS OF 2', 3'-DIDEOXYNUCLEOSIDES FOR AUTOMATED DNA SYNTHESIS AND PYROPHOSPHOROLYSIS ACTIVATED POLYMERIZATION | DCTD, MTAP, RNGTT | HPGD 840/4885XDH 3045/4885TYMP 10/4885 |
| US-20160108079-A1 | Synthesis Of 2',3'-Dideoxynucleosides For Automated DNA Synthesis And Pyrophosphorolysis Activated Polymerization | DCTD, MTAP, RNGTT | HPGD 840/4885XDH 3045/4885TYMP 10/4885 |
| US-20110294122-A1 | Synthesis of 2', 3'-Dideoxynucleosides for Automated DNA Synthesis and Pyrophosphorolysis Activated Polymerization | DCTD, MTAP, RNGTT | HPGD 840/4885XDH 3045/4885TYMP 10/4885 |
| US-20150045547-A1 | Synthesis Of 2' , 3' -Dideoxynucleosides For Automated DNA Synthesis And Pyrophosphorolysis Activated Polymerization | DCTD, MTAP, RNGTT | HPGD 840/4885XDH 3045/4885TYMP 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.