Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2085543 | 0.81 | KMT2A (0.56) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL5630057 | 0.79 | KMT2A (0.54) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL14568525 | 0.79 | MEN1 (0.54) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL2946787 | 0.79 | KMT2A (0.54) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL13544509 | 0.78 | MEN1 (0.53) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL13808926 | 0.78 | ALDH1A1 (0.70) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL18835454 | 0.77 | MEN1 (0.52) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL13544722 | 0.77 | SMYD3 (0.52) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL29138050 | 0.77 | KMT2A (0.52) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL28684619 | 0.76 | NPC1 (0.66) | MAPTMEN1KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011084985-A1 | CXCR3 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-14 | — | — | WO | disclosed |