Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | HPGDS | O60760 | 3/20 | 0.35 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.35 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.34 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.34 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1431709 | 0.83 | HTR2B (0.37) | PIK3CDPIK3CBGSK3BPIK3CGPIM1 | |
| SCHEMBL459027 | 0.82 | HTR6 (0.41) | PIK3CDPIK3CBGSK3BPIK3CGPIM1 | |
| SCHEMBL1251686 | 0.80 | PIK3CD (0.62) | PIK3CDPIK3CBGSK3BPIK3CGPIM1 | |
| SCHEMBL470164 | 0.78 | HTR6 (0.37) | PIK3CDPIK3CBGSK3BPIK3CGPIM1 | |
| SCHEMBL463569 | 0.78 | HTR6 (0.39) | PIK3CDPIK3CBGSK3BPIK3CGPIM1 | |
| SCHEMBL459116 | 0.76 | PIK3CD (0.59) | PIK3CDPIK3CBGSK3BPIK3CGPIM1 | |
| SCHEMBL716071 | 0.75 | ATR (0.35) | PIK3CDPIK3CBGSK3BPIK3CGPIM1 | |
| SCHEMBL717170 | 0.74 | PIP4K2A (0.35) | PIK3CDPIK3CBGSK3BPIK3CGPIM1 | |
| SCHEMBL1431711 | 0.74 | PIK3CD (0.51) | PIK3CDPIK3CBGSK3BPIK3CGPIM1 | |
| SCHEMBL1779260 | 0.73 | PIK3CD (0.49) | PIK3CDPIK3CBGSK3BPIK3CGPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280959-A1 | NOVEL COMPOUNDS | Glaxo Group Limited (GB) | 2011-02-09 | — | — | EP | disclosed |