Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 7/20 | 0.59 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.59 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.59 |
| ▸ | PIM1 | P11309 | 2/20 | 0.59 |
| ▸ | GSK3B | P49841 | 2/20 | 0.59 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 2/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | TEC | P42680 | 1/20 | 0.40 |
| ▸ | TXK | P42681 | 1/20 | 0.40 |
| ▸ | BLK | P51451 | 1/20 | 0.40 |
| ▸ | BMX | P51813 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1119167 | 0.84 | PIK3CD (0.56) | PIK3CDPIK3CBPIK3CGPIK3CAPIM1 | |
| SCHEMBL462946 | 0.81 | METAP2 (0.48) | PIK3CDPIK3CBPIK3CGPIK3CAGSK3B | |
| SCHEMBL1118909 | 0.81 | PIK3CD (0.53) | PIK3CDPIK3CBPIK3CGPIK3CAPIM1 | |
| SCHEMBL1431437 | 0.81 | PIK3CD (0.55) | PIK3CDPIK3CBPIK3CGPIK3CAPIM1 | |
| SCHEMBL1430757 | 0.80 | PIK3CD (0.49) | PIK3CDPIK3CBPIK3CGPIK3CAPIM1 | |
| SCHEMBL457583 | 0.79 | PIK3CD (0.74) | PIK3CDPIK3CBPIK3CGPIK3CAPIM1 | |
| SCHEMBL461789 | 0.78 | PIK3CD (0.48) | PIK3CDPIK3CBPIK3CGPIK3CAPIM1 | |
| SCHEMBL1431305 | 0.78 | PIK3CD (0.55) | PIK3CDPIK3CBPIK3CGPIK3CAPIM1 | |
| SCHEMBL1778790 | 0.77 | PIK3CD (0.74) | PIK3CDPIK3CBPIK3CGPIK3CAPIM1 | |
| SCHEMBL1250243 | 0.77 | PIK3CD (0.74) | PIK3CDPIK3CBPIK3CGPIK3CAPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280959-A1 | NOVEL COMPOUNDS | Glaxo Group Limited (GB) | 2011-02-09 | — | — | EP | disclosed |