Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 16/20 | 0.53 |
| ▸ | KDM6B | O15054 | 7/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | KDM4D | Q6B0I6 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KDM4A | O75164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162018 | 0.81 | SIRT3 (0.56) | KDM4CKDM6BKMT2ATDP1L3MBTL1 | |
| SCHEMBL30138224 | 0.81 | SIRT3 (0.56) | KDM4CKDM6BKMT2ATDP1L3MBTL1 | |
| SCHEMBL17439049 | 0.81 | KDM5A (0.48) | KDM4CKDM6BKDM4EMEN1ALDH1A1 | |
| SCHEMBL894396 | 0.81 | KDM4C (0.56) | KDM4CKDM6BUSP2KDM4DKDM4E | |
| SCHEMBL19439267 | 0.81 | KDM4C (0.61) | KDM4CKDM6BUSP2KDM4DKDM4E | |
| SCHEMBL17438513 | 0.80 | KDM5A (0.47) | KDM4CKDM6BKDM4EMEN1ALDH1A1 | |
| SCHEMBL14917464 | 0.80 | KDM4E (0.46) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL4673791 | 0.80 | KDM4E (0.58) | KDM4CKDM6BKDM4DKDM4EKDM4A | |
| SCHEMBL28257295 | 0.79 | LMNA (0.44) | KDM4CKDM6BKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL7224946 | 0.79 | KDM5A (0.43) | KDM4CKDM6BKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884070-A | PYRIDYL DERIVATIVES AS BROMODOMAIN INHIBITORS | 葛兰素史克知识产权第二有限公司 | 2018-11-23 | — | — | CN | disclosed |
| WO-2011085454-A1 | GP120 -BINDING BENZENE COMPOUNDS AND SACCHARIDE COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN K.U.LEUVEN R&D (BE) | 2011-07-21 | — | — | WO | disclosed |