Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12517711 | 0.87 | HRH3 (0.38) | HRH3FFAR1 | |
| SCHEMBL14901574 | 0.82 | CA12 (0.41) | CA12CA9MAOAMAOBCA1 | |
| SCHEMBL12517391 | 0.72 | NR1H2 (0.52) | MAOBCA2 | |
| SCHEMBL31725799 | 0.70 | CA12 (0.45) | CA12CA9MAOAMAOBCA1 | |
| SCHEMBL2530176 | 0.70 | KCNA3 (0.50) | — | |
| SCHEMBL962262 | 0.70 | HRH3 (0.55) | HRH3FFAR1CA2 | |
| SCHEMBL10733620 | 0.70 | FFAR1 (0.56) | FFAR1CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL15977888 | 0.69 | KCNA3 (0.38) | HRH3CA12CA9CA1CA2 | |
| SCHEMBL13595406 | 0.69 | LTA4H (0.42) | — | |
| SCHEMBL21483679 | 0.68 | LTA4H (0.57) | HRH3FFAR1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011082488-A1 | BISPHENOL DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2011-07-14 | — | — | WO | disclosed |