Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 8/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12313958 | 0.80 | CA12 (0.49) | LTA4HAPPTAAR1PLA2G2A | |
| SCHEMBL24629374 | 0.79 | MAOB (0.45) | APPTAAR1 | |
| SCHEMBL1263392 | 0.79 | LTA4H (0.46) | LTA4HMEN1USP2ALDH1A1LMNA | |
| SCHEMBL21100939 | 0.78 | KEAP1 (0.55) | LTA4HAPPTAAR1PLA2G2A | |
| Hydrochloric Acid SCHEMBL1262643 | 0.78 | MAOB (0.45) | LTA4HMEN1USP2ALDH1A1LMNA | |
| SCHEMBL17806191 | 0.75 | MEN1 (0.71) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL17806184 | 0.75 | MEN1 (0.71) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL23798500 | 0.75 | APP (0.49) | LTA4HMEN1USP2ALDH1A1LMNA | |
| SCHEMBL23799321 | 0.75 | LTA4H (0.49) | LTA4HMEN1USP2ALDH1A1LMNA | |
| SCHEMBL23291296 | 0.73 | APP (0.61) | MEN1USP2ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638558-B2 | drug loaded micelle of a triblock polymer tert-butylphenylsilylpropene-polyethylene glycol-b-poly(tert-butylaspartic acid-b-polyphenylalanine-copoly( tert-buyltyrosine) has a drug-loaded inner core, a crosslinked outer core, and a hydrophilic shell | INTEZYNE TECHNOLOGIES, INC. (US) | 2009-12-29 | — | — | US | disclosed |