Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRND | Q07001 | 6/20 | 0.70 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.70 |
| ▸ | CHRNG | P07510 | 2/20 | 0.70 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.70 |
| ▸ | GRIA1 | P42261 | 8/20 | 0.67 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.66 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.66 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.66 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.66 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.66 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.66 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21346955 | 0.91 | GRIA1 (0.74) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL6574815 | 0.88 | PTPN1 (0.66) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL6574821 | 0.88 | PTPN1 (0.66) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL23086284 | 0.87 | PTPN1 (0.68) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL6020146 | 0.84 | CTSL (0.67) | CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL19619302 | 0.83 | CHRND (0.56) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL15788809 | 0.83 | CHRND (0.59) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL6021465 | 0.83 | CTSL (0.54) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL14761409 | 0.83 | CHRNB2 (0.64) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL14765234 | 0.83 | CHRNB2 (0.64) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012121610-A1 | IN VIVO METHODS OF MONITORING BIODISTRIBUTION | BOVIN NIKOLAI VLADIMIROVICH (RU) | 2012-09-13 | — | — | WO | disclosed |