Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.32 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.32 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BRD1 | O95696 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20630906 | 0.90 | MEN1 (0.38) | MEN1KMT2AL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL12526114 | 0.84 | MEN1 (0.43) | MEN1KMT2AL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL20631606 | 0.81 | MEN1 (0.38) | MEN1KMT2AL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL12528173 | 0.79 | ADRA1D (0.38) | MEN1KMT2AL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL20607667 | 0.78 | MEN1 (0.43) | MEN1KMT2AL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL20630853 | 0.74 | MEN1 (0.32) | MEN1KMT2AL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL12525205 | 0.74 | MEN1 (0.44) | MEN1KMT2AL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL12495572 | 0.73 | PIK3CA (0.50) | MEN1KMT2AL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL12494814 | 0.73 | PIK3CA (0.50) | MEN1KMT2AL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL20631611 | 0.71 | HDAC3 (0.46) | MEN1KMT2AL3MBTL1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012120141-A1 | Π (PI)-CONJUGATED FLUOROIONOPHORES AND METHOD FOR DETERMINING AN ALKALI ION | UNIVERSITÄT POTSDAM (DE) | 2012-09-13 | — | — | WO | disclosed |