Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 10/20 | 0.35 |
| ▸ | MEN1 | O00255 | 7/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 6/20 | 0.35 |
| ▸ | HTT | P42858 | 5/20 | 0.35 |
| ▸ | ATM | Q13315 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12528167 | 0.92 | CASP1 (0.35) | ADRA1DADRA1AADRA1BMAPTMEN1 | |
| SCHEMBL20630860 | 0.91 | ADRA1D (0.42) | ADRA1DADRA1AADRA1BMAPTMEN1 | |
| SCHEMBL12495579 | 0.85 | ADRA1D (0.47) | ADRA1DADRA1AADRA1BMAPTMEN1 | |
| SCHEMBL20630368 | 0.85 | CASP1 (0.38) | ADRA1DADRA1AADRA1BMAPTMEN1 | |
| SCHEMBL12527288 | 0.81 | ADRA1D (0.40) | ADRA1DADRA1AADRA1BMAPTMEN1 | |
| SCHEMBL20631468 | 0.79 | ADRA1A (0.48) | ADRA1DADRA1AADRA1BMAPTMEN1 | |
| SCHEMBL12527293 | 0.79 | MEN1 (0.33) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL12495141 | 0.79 | CASP1 (0.43) | ADRA1DADRA1AADRA1BMAPTMEN1 | |
| SCHEMBL12495445 | 0.75 | CYP19A1 (0.53) | MAPTMEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL12495402 | 0.75 | CYP19A1 (0.53) | MAPTMEN1KMT2AKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012120141-A1 | Π (PI)-CONJUGATED FLUOROIONOPHORES AND METHOD FOR DETERMINING AN ALKALI ION | UNIVERSITÄT POTSDAM (DE) | 2012-09-13 | — | — | WO | disclosed |