SCHEMBL12528566

SCHEMBL12528566

Clc1ccccc1-n1ccc(-c2ccccc2)n1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.58
KMT2A Q03164 2/20 0.48
SCN9A Q15858 2/20 0.41
CAPN1 P07384 1/20 0.41
KDM4E B2RXH2 3/20 0.40
HSD17B10 Q99714 1/20 0.40
ALDH1A1 P00352 4/20 0.39
HPGD P15428 3/20 0.39
MAPT P10636 2/20 0.39
HTT P42858 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
NOTUM Q6P988 1/20 0.38
MEN1 O00255 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CYP2A6 P11509 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27796122 0.79 KMT2A (0.48) KMT2ACAPN1KDM4EHSD17B10ALDH1A1
SCHEMBL21141881 0.79 KMT2A (0.53) KMT2ACAPN1KDM4EHSD17B10ALDH1A1
SCHEMBL950145 0.77 CAPN1 (0.45) KMT2ACAPN1
SCHEMBL30987383 0.76 NPC1 (0.51) KMT2ACAPN1KDM4EHSD17B10ALDH1A1
SCHEMBL29007617 0.76 KMT2A (0.50) KMT2ACAPN1HSD17B10ALDH1A1HPGD
SCHEMBL28001364 0.75 KMT2A (0.48) KMT2AKDM4EHSD17B10ALDH1A1MAPT
SCHEMBL218118 0.75 KMT2A (0.57) KMT2AKDM4EHSD17B10ALDH1A1HPGD
SCHEMBL12528199 0.74 BCHE (0.41) BCHEKMT2AALDH1A1HTTNPSR1
SCHEMBL2615993 0.74 MAPT (0.52) BCHEKDM4EALDH1A1MAPTHTT
SCHEMBL2359053 0.74 BCHE (0.41) BCHEKMT2AALDH1A1HTTNOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968573-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-28 US disclosed
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME IKEGAMI HIROSHI 2011-03-24 US disclosed
US-7867949-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-11 US disclosed
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME ACHE, H1-2, H1-0 BCHE 19/4885KMT2A 404/4885SCN9A 488/4885
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same ACHE, DDT, CAT BCHE 9/4885KMT2A 1294/4885SCN9A 558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.