Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL10418488 | 0.98 | KMT2A (0.55) | KMT2AHTTCYP2C9HPGDALDH1A1 | |
| SCHEMBL17279816 | 0.90 | KMT2A (0.52) | KMT2AHTTCYP2C9HPGDALDH1A1 | |
| SCHEMBL17279826 | 0.90 | ALDH1A1 (0.48) | KMT2AHTTCYP2C9HPGDALDH1A1 | |
| Formamide SCHEMBL29227819 | 0.89 | HTT (0.48) | KMT2AHTTCYP2C9HPGDALDH1A1 | |
| SCHEMBL15072164 | 0.88 | KMT2A (0.50) | KMT2AHTTCYP2C9HPGDALDH1A1 | |
| SCHEMBL2148390 | 0.88 | ALDH1A1 (0.46) | KMT2AHTTCYP2C9HPGDALDH1A1 | |
| SCHEMBL13679138 | 0.87 | HTT (0.65) | KMT2AHTTCYP2C9HPGDALDH1A1 | |
| SCHEMBL4308671 | 0.87 | KMT2A (0.48) | KMT2AHTTCYP2C9ALDH1A1SMN1; SMN2 | |
| SCHEMBL15060395 | 0.87 | NPC1 (0.50) | KMT2AHTTALDH1A1MAPTKDM4E | |
| SCHEMBL29007611 | 0.87 | HTT (0.65) | KMT2AHTTCYP2C9HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 349 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12617771-B2 | Diphenylpyrazole compound, and preparation method therefor and application thereof | NORTHWEST A&F UNIVERSITY (CN) | 2026-05-05 | — | — | US | claimed |
| CN-119055639-A | Application of diphenylpyrazole compound in preparation of medicine for treating tuberculosis | 西北农林科技大学 | 2024-12-03 | — | — | CN | claimed |
| CN-118678881-A | Application of diphenylpyrazole compound as herbicide synergist | 西北农林科技大学 | 2024-09-20 | — | — | CN | claimed |
| CN-118591293-A | Weeding composition | 西北农林科技大学 | 2024-09-03 | — | — | CN | claimed |
| US-20240083871-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | NORTHWEST A&F UNIVERSITY (CN) | 2024-03-14 | — | — | US | claimed |
| CN-117658918-A | Application of diphenylpyrazole compound | 西北农林科技大学 | 2024-03-08 | — | — | CN | claimed |
| CN-114716409-B | Diphenyl pyrazole compound and preparation method and application thereof | 西北农林科技大学 | 2024-01-12 | — | — | CN | claimed |
| WO-2023202545-A1 | USE OF DIPHENYL PYRAZOLE COMPOUND AS HERBICIDE SYNERGIST | 西北农林科技大学 | 2023-10-26 | — | — | WO | claimed |
| CN-112724086-B | Preparation method of 5-amino-4-nitrile-1, 3-diphenylpyrazole | 三峡大学 | 2022-09-02 | — | — | CN | claimed |
| CN-114716409-A | Diphenyl pyrazole compound and preparation method and application thereof | 西北农林科技大学 | 2022-07-08 | — | — | CN | claimed |
| EP-1713484-A2 | COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2006-10-25 | — | — | EP | claimed |
| EP-1711495-A2 | QUINOLINE, QUINAZOLINE, PYRIDINE AND PYRIMIDINE COUNDS AND THEIR USE IN THE TREATMENT OF INFLAMMATION, ANGIOGENESIS AND CANCER | AMGEN INC. (US) | 2006-10-18 | — | — | EP | claimed |
| US-20050245547-A1 | 6-((6,7-Bis(methoxy)-4-quinolinyl)oxy)-N-(3-methylphenyl)-1-benzofuran-3-carboxamide;antiproliferative; -metastasis; -carcinogenic; -tumor; -inflammatory; -arthritic agents;hypotensive agents; myocardium necrosis; rheumatic diseases; tyrosine kinase inhibitors; antiallergens; asthma | AMGEN INC. | 2005-11-03 | — | — | US | claimed |
| WO-2005073224-A2 | QUINOLINE QUINAZOLINE PYRIDINE AND PYRIMIDINE COUNDS AND THEIR USE IN THE TREATMENT OF INFLAMMATION ANGIOGENESIS AND CANCER | AMGEN INC (US) | 2005-08-11 | — | — | WO | claimed |
| WO-2005070891-A2 | COMPOUNDS AND METHODS OF USE | AMGEN INC (US) | 2005-08-04 | — | — | WO | claimed |
| EP-1141207-B1 | TRANSPARENT/TRANSLUCENT LIQUID ENZYME COMPOSITIONS IN CLEAR BOTTLES COMPRISING FLUORESCENT DYE OR UV ABSORBER | UNILEVER NV (NL) | 2004-02-04 | — | — | EP | claimed |
| EP-1141213-B1 | TRANSPARENT/TRANSLUCENT LIQUID COMPOSITIONS IN CLEAR BOTTLES COMPRISING COLORANT AND FLUORESCENT DYE OR UV ABSORBER | UNILEVER NV (NL) | 2004-02-04 | — | — | EP | claimed |
| EP-1047729-B1 | COMPOSITION FOR BLEACHING MECHANICAL PULP | DE DONATO FAUSTO (IT) | 2003-01-08 | — | — | EP | claimed |
| EP-0731796-A1 | 1,3,5-TRISUBSTITUTED PYRAZOLE COMPOUNDS FOR TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-09-18 | — | — | EP | claimed |
| WO-1995015318-A1 | 1,3,5-TRISUBSTITUTED PYRAZOLE COMPOUNDS FOR TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-06-08 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245547-A1 | 6-((6,7-Bis(methoxy)-4-quinolinyl)oxy)-N-(3-methylphenyl)-1-benzofuran-3-carboxamide;antiproliferative; -metastasis; -carcinogenic; -tumor; -inflammatory; -arthritic agents;hypotensive agents; myocardium necrosis; rheumatic diseases; tyrosine kinase inhibitors; antiallergens; asthma | HGF, MET, HGFAC | KMT2A 2053/4885HTT 1534/4885CYP2C9 1651/4885 |
| US-12617771-B2 | Diphenylpyrazole compound, and preparation method therefor and application thereof | GSTP1, GSTO1, GSTA1 | KMT2A 4050/4885HTT 4506/4885CYP2C9 89/4885 |
| US-20240083871-A1 | DIPHENYLPYRAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | GSTP1, CYP4F11, GSTA1 | KMT2A 3071/4885HTT 4122/4885CYP2C9 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.