SCHEMBL12528592

SCHEMBL12528592

Cc1cc(Cl)cc(C(=O)N(C)C)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.80

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ DHODH Q02127 3/20 0.43
▸ MALT1 Q9UDY8 4/20 0.36
▸ F10 P00742 2/20 0.34
▸ EDNRA P25101 1/20 0.34
▸ NTRK1 P04629 1/20 0.34
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ TRPV1 Q8NER1 1/20 0.32
▸ CNR2 P34972 1/20 0.32
▸ PSD A5PKW4 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ DRD4 P21917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL951174 0.94 DHODH (0.43) DHODHMALT1F10NTRK1TRPV1
SCHEMBL10028783 0.93 DHODH (0.41) DHODHMALT1F10NTRK1MEN1
SCHEMBL951424 0.92 DHODH (0.42) DHODHMALT1F10TRPV1PSD
SCHEMBL13318598 0.92 DHODH (0.40) DHODHMALT1F10NTRK1MEN1
SCHEMBL6120929 0.91 DHODH (0.43) DHODHMALT1F10NTRK1MEN1
SCHEMBL12527884 0.91 DHODH (0.41) DHODHMALT1F10TRPV1PSD
SCHEMBL2594967 0.91 DHODH (0.41) DHODHMALT1F10NTRK1MEN1
SCHEMBL30978015 0.91 DHODH (0.41) DHODHMALT1F10NTRK1MEN1
SCHEMBL12528144 0.91 F10 (0.42) DHODHMALT1F10MEN1KMT2A
SCHEMBL902720 0.91 DHODH (0.46) DHODHMALT1F10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968573-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-28 — — US disclosed
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME IKEGAMI HIROSHI 2011-03-24 — — US disclosed
US-7867949-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-11 — — US disclosed
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME ACHE, H1-2, H1-0 DHODH 771/4885MALT1 4856/4885F10 2564/4885
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same ACHE, DDT, CAT DHODH 284/4885MALT1 4865/4885F10 3713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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