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Sugi Predict / Compounds / SCHEMBL951424

SCHEMBL951424

SCHEMBL951424

CNN(C)C(=O)c1cc(Cl)cc(C)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.79

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ DHODH Q02127 3/20 0.42
▸ MALT1 Q9UDY8 5/20 0.35
▸ TP53 P04637 2/20 0.31
▸ GAA P10253 2/20 0.31
▸ MAPT P10636 1/20 0.31
▸ TRPV1 Q8NER1 1/20 0.31
▸ PSD A5PKW4 1/20 0.31
▸ DRD4 P21917 1/20 0.30
▸ F10 P00742 1/20 0.30
▸ S1PR1 P21453 1/20 0.30
▸ S1PR3 Q99500 1/20 0.30
▸ SMN1; SMN2 Q16637 1/20 0.30
▸ HDAC9 Q9UKV0 1/20 0.30
▸ NPC1 O15118 1/20 0.30
▸ HTT P42858 1/20 0.30
▸ RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12911768 0.94 DHODH (0.42) DHODHMALT1GAA
SCHEMBL950951 0.93 DHODH (0.40) DHODHMALT1TRPV1PSD
SCHEMBL6120929 0.92 DHODH (0.43) DHODHMALT1TRPV1PSDDRD4
SCHEMBL12528592 0.92 DHODH (0.43) DHODHMALT1TRPV1PSDDRD4
SCHEMBL12559352 0.92 DHODH (0.41) DHODHMALT1TRPV1PSD
SCHEMBL951174 0.91 DHODH (0.43) DHODHMALT1TRPV1PSDDRD4
SCHEMBL13073078 0.91 DHODH (0.40) DHODHMALT1
SCHEMBL13318598 0.91 DHODH (0.40) DHODHMALT1F10
SCHEMBL121150 0.90 DHODH (0.40) DHODHMALT1
SCHEMBL951370 0.90 DHODH (0.40) DHODHMALT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2793578-B1 N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2018-06-06 — — EP claimed
US-20140013654-A1 Foamable Pesticide Compositions BASF CORPORATION 2014-01-16 — — US claimed
US-20130012386-A1 Methods For Controlling Pests BASF CORPORATION (US) 2013-01-10 — — US claimed
WO-2021048188-A1 HIGHLY EFFECTIVE FORMULATIONS ON THE BASIS OF 2-[(2,4-DICHLORPHENYL)-METHYL]-4,4'-DIMETHYL-3-ISOXAZOLIDINONES AND PREEMERGENCE HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2021-03-18 — — WO disclosed
EP-3113618-A1 HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS Bayer CropScience Aktiengesellschaft (DE) 2017-01-11 — — EP disclosed
WO-2015132313-A1 HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS BAYER CROPSCIENCE AG (DE) 2015-09-11 — — WO disclosed
US-7968573-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-28 — — US disclosed
EP-1937664-B1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2011-06-15 — — EP disclosed
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME IKEGAMI HIROSHI 2011-03-24 — — US disclosed
US-7867949-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-11 — — US disclosed
US-7867949-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-11 — — US disclosed
EP-2251336-A1 Hydrazide compounds as intermediates of pesticides Sumitomo Chemical Company, Limited (JP) 2010-11-17 — — EP disclosed
EP-2251336-A1 Hydrazide compounds as intermediates of pesticides Sumitomo Chemical Company, Limited (JP) 2010-11-17 — — EP disclosed
US-20100137314-A1 HARMFUL ORGANISM CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 — — US disclosed
US-20100099692-A1 HARMFUL ORGANISM CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-22 — — US disclosed
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-16 — — US disclosed
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-16 — — US disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099692-A1 HARMFUL ORGANISM CONTROL COMPOSITION UQCRC1, UQCRC2, Q6ZSR9 DHODH 277/4885MALT1 4850/4885TP53 2470/4885
US-20130012386-A1 Methods For Controlling Pests DDT, ACHE, PON1 DHODH 1877/4885MALT1 4338/4885TP53 3940/4885
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME ACHE, H1-2, H1-0 DHODH 771/4885MALT1 4856/4885TP53 4303/4885
US-20100137314-A1 HARMFUL ORGANISM CONTROL COMPOSITION UQCRC2, UQCRC1, UQCRB DHODH 558/4885MALT1 4804/4885TP53 1707/4885
US-20140013654-A1 Foamable Pesticide Compositions DDT, PON1, ACHE DHODH 718/4885MALT1 4476/4885TP53 2145/4885
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same ACHE, DDT, CAT DHODH 284/4885MALT1 4865/4885TP53 4742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.