Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13122619 | 1.00 | CTNNB1 (0.56) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL30885150 | 0.83 | CTNNB1 (0.52) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL30885174 | 0.83 | CTNNB1 (0.52) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL7272663 | 0.81 | CTNNB1 (0.75) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL6677809 | 0.80 | CTNNB1 (0.63) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL10170673 | 0.78 | CTNNB1 (0.61) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL1826710 | 0.78 | CTNNB1 (0.61) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL2684738 | 0.78 | CTNNB1 (0.61) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL16017641 | 0.77 | CTNNB1 (0.59) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL851631 | 0.77 | PPARG (0.48) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2327765-A1 | Nitrilases | Verenium Corporation (US) | 2011-06-01 | — | — | EP | disclosed |
| EP-2327767-A1 | Nitrilases | Verenium Corporation (US) | 2011-06-01 | — | — | EP | disclosed |
| EP-2327766-A1 | Nitrilases | Verenium Corporation (US) | 2011-06-01 | — | — | EP | disclosed |
| EP-2319919-A1 | Nitrilases | Verenium Corporation (US) | 2011-05-11 | — | — | EP | disclosed |