Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL27478083 | 0.87 | CTNNB1 (0.41) | CTNNB1TDP1SLC1A3SLC1A2SLC1A1 | |
| Leucine SCHEMBL27470090 | 0.84 | CTNNB1 (0.39) | CTNNB1TDP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7065955 | 0.84 | PSMB5 (0.43) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| Leucine SCHEMBL2294646 | 0.84 | CTNNB1 (0.39) | CTNNB1TDP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL12532011 | 0.83 | CTNNB1 (0.56) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL13122619 | 0.83 | CTNNB1 (0.56) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL28094779 | 0.83 | KMT2A (0.50) | CTNNB1TDP1HRH4CYP1A2CYP2D6 | |
| Water SCHEMBL28094441 | 0.82 | KMT2A (0.49) | CTNNB1TDP1HRH4CYP1A2CYP2D6 | |
| SCHEMBL30885150 | 0.79 | CTNNB1 (0.52) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL6447307 | 0.78 | CTNNB1 (0.54) | CTNNB1TDP1HRH4SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12419832-B2 | Intratumoral delivery of bortezomib | COGNOS THERAPEUTICS, INC. (US) | 2025-09-23 | — | — | US | disclosed |