SCHEMBL125327

SCHEMBL125327

CCCCN(CO)c1nc(N(CO)CCCC)nc(N(CO)CCCC)n1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 6/20 0.42
CRHR1 P34998 5/20 0.41
MAPT P10636 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
LMNA P02545 1/20 0.36
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ELANE P08246 1/20 0.33
ALDH1A1 P00352 1/20 0.32
HTT P42858 1/20 0.32
NCOA1 Q15788 1/20 0.32
NCOA3 Q9Y6Q9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL660741 0.96 SLC29A1 (0.44) SLC29A1CRHR1MAPTSMN1; SMN2LMNA
SCHEMBL10955955 0.86 SLC29A1 (0.41) SLC29A1CRHR1MAPTLMNAMEN1
SCHEMBL22722482 0.86 MAPT (0.52) SLC29A1CRHR1MAPTSMN1; SMN2TSHR
SCHEMBL5355585 0.85 MAPT (0.50) SLC29A1CRHR1MAPTSMN1; SMN2LMNA
SCHEMBL2841753 0.84 SLC29A1 (0.57) SLC29A1CRHR1MAPTSMN1; SMN2LMNA
Butyl Alcohol SCHEMBL9418922 0.82 ALDH1A1 (0.50) SLC29A1CRHR1MAPTSMN1; SMN2LMNA
SCHEMBL11588785 0.82 SLC29A1 (0.35) SLC29A1CRHR1MAPTSMN1; SMN2LMNA
SCHEMBL21081373 0.81 MAPT (0.47) SLC29A1CRHR1MAPTSMN1; SMN2LMNA
1-Pentanol SCHEMBL28653250 0.80 SMN1; SMN2 (0.52) SLC29A1CRHR1MAPTSMN1; SMN2LMNA
SCHEMBL2535675 0.78 MAPT (0.48) SLC29A1CRHR1MAPTSMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 496 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11629207-B2 Rubber composition and a tire THE GOODYEAR TIRE & RUBBER COMPANY 2023-04-18 US claimed
US-20210179748-A1 RUBBER COMPOSITION AND A TIRE THE GOODYEAR TIRE & RUBBER COMPANY, 2021-06-17 US claimed
EP-3835350-A2 A RUBBER COMPOSITION AND A TIRE The Goodyear Tire & Rubber Company (US) 2021-06-16 EP claimed
EP-3040212-B1 PNEUMATIC TIRE GOODYEAR TIRE & RUBBER (US) 2017-10-18 EP claimed
US-9556351-B2 Rubber composition suitable for use as a cap ply in a tire Bridgestone Americas Tire Operations, Inc. (US) 2017-01-31 US claimed
US-9441325-B2 Atmospheric plasma treatment of reinforcement cords and use in rubber articles THE GOODYEAR TIRE & RUBBER COMPANY (US) 2016-09-13 US claimed
EP-3040212-A1 PNEUMATIC TIRE The Goodyear Tire & Rubber Company (US) 2016-07-06 EP claimed
US-20160167449-A1 PNEUMATIC TIRE GOODYEAR TIRE & RUBBER COMPANY, THE 2016-06-16 US claimed
US-20160040024-A1 RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2016-02-11 US claimed
US-9163127-B2 Rubber composition suitable for use as a cap ply in a tire BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2015-10-20 US claimed
US-5300585-A Having improved cure reversion THE GOODYEAR TIRE & RUBBER COMPANY (US) 1994-04-05 US claimed
EP-0553678-A1 Rubber stock containing a polyhydric phenoxy resin THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-08-04 EP claimed
US-5229459-A bonding strength THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-07-20 US claimed
US-5206289-A Rubber stock containing a polyhydric phenoxy resin THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-04-27 US claimed
EP-0537639-A1 Rubber stock containing high trans polybutadiene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-04-21 EP claimed
US-5194513-A As methylene acceptor in place of resorcinol and a methylene donor; improved rebound in tires THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-03-16 US claimed
EP-0476310-A2 Rubber compositions containing a hydroxy aryl substituted maleamic acid THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-03-25 EP claimed
EP-0475222-A1 Sulfur vulcanizable rubber compositions containing N,N'-(M-Phenylene)bismaleimide THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-03-18 EP claimed
US-5091449-A Improved tear strength, adhesion THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-02-25 US claimed
US-5049618-A Bonding reinforcement THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-09-17 US claimed