SCHEMBL660741

SCHEMBL660741

CCCCN(CO)c1nc(N(CO)CO)nc(N(CCCC)CCCC)n1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 8/20 0.44
MAPT P10636 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CRHR1 P34998 5/20 0.40
LMNA P02545 1/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ELANE P08246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL125327 0.96 SLC29A1 (0.42) SLC29A1MAPTSMN1; SMN2CRHR1LMNA
SCHEMBL5355585 0.87 MAPT (0.50) SLC29A1MAPTSMN1; SMN2CRHR1LMNA
SCHEMBL2841753 0.85 SLC29A1 (0.57) SLC29A1MAPTSMN1; SMN2CRHR1LMNA
Butyl Alcohol SCHEMBL9418922 0.83 ALDH1A1 (0.50) SLC29A1MAPTSMN1; SMN2CRHR1LMNA
SCHEMBL10955955 0.82 SLC29A1 (0.41) SLC29A1MAPTCRHR1LMNAMEN1
SCHEMBL22722482 0.82 MAPT (0.52) SLC29A1MAPTSMN1; SMN2CRHR1TSHR
SCHEMBL21081373 0.82 MAPT (0.47) SLC29A1MAPTSMN1; SMN2CRHR1LMNA
SCHEMBL11588785 0.82 SLC29A1 (0.35) SLC29A1MAPTSMN1; SMN2CRHR1LMNA
1-Pentanol SCHEMBL28653250 0.81 SMN1; SMN2 (0.52) SLC29A1MAPTSMN1; SMN2CRHR1LMNA
SCHEMBL2535675 0.80 MAPT (0.48) SLC29A1MAPTSMN1; SMN2CRHR1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9163127-B2 Rubber composition suitable for use as a cap ply in a tire BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2015-10-20 US disclosed
US-20140005320-A1 RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2014-01-02 US disclosed
US-8137024-B2 Hydrocarbon-adsorbing porous pavement structure Reynolds Presto Products Inc. (US) 2012-03-20 US disclosed
US-20120045280-A1 HYDROCARBON-ADSORBING POROUS PAVEMENT STRUCTURE REYNOLDS CONSUMER PRODUCTS, INC. D/B/A PRESTO PRODUCTS COMPANY (US) 2012-02-23 US disclosed
EP-1186595-B1 Diaryl-p-phenylenediamine disulfides GOODYEAR TIRE & RUBBER (US) 2003-11-26 EP disclosed
EP-0149955-B1 CUSHION STOCK FOR POWER TRANSMISSION BELTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-09-30 EP disclosed
US-4634726-A IMPROVED DURABILITY THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-01-06 US disclosed
EP-0149955-A2 Cushion stock for power transmission belts THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-07-31 EP disclosed