SCHEMBL12533800

SCHEMBL12533800

Cc1ccc(N(c2ccc(C)cc2)c2ccc(C=CC(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.82
CYP3A4 P08684 3/20 0.82
ALDH1A1 P00352 1/20 0.82
HPGD P15428 1/20 0.82
CYP1B1 Q16678 4/20 0.71
MAOB P27338 6/20 0.62
BCHE P06276 2/20 0.62
PLIN1 O60240 1/20 0.62
LMNA P02545 1/20 0.62
TNFRSF1A P19438 1/20 0.62
ACHE P22303 1/20 0.62
RECQL P46063 1/20 0.62
PLIN5 Q00G26 1/20 0.62
ABHD5 Q8WTS1 1/20 0.62
RAB9A P51151 4/20 0.61
KMT2A Q03164 3/20 0.61
NPC1 O15118 2/20 0.61
CASP3 P42574 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
SENP8 Q96LD8 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9718504 0.91 MAPT (0.70) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL9718506 0.91 MAPT (0.70) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL6200952 0.91 MAPT (1.00) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL76030 0.91 MAPT (1.00) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL5753797 0.91 MAPT (1.00) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL9718496 0.87 CYP1B1 (0.69) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL9718492 0.87 CYP1B1 (0.69) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL27977352 0.86 MAPT (0.90) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL23789072 0.84 MAPT (0.87) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL11694297 0.84 CYP1B1 (0.73) MAPTCYP3A4ALDH1A1HPGDCYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7955768-B2 Electrophotographic photoconductor and method for producing the same, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2011-06-07 US disclosed
US-7955768-B2 Electrophotographic photoconductor and method for producing the same, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2011-06-07 US disclosed
US-20090035017-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND METHOD FOR PRODUCING THE SAME, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2009-02-05 US disclosed
US-20090035017-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND METHOD FOR PRODUCING THE SAME, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2009-02-05 US disclosed