SCHEMBL5753797

SCHEMBL5753797

Cc1ccc(C=CC(=O)c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 1.00
CYP3A4 P08684 3/20 1.00
ALDH1A1 P00352 2/20 1.00
HPGD P15428 1/20 1.00
CYP1B1 Q16678 3/20 0.86
MAOB P27338 6/20 0.75
BCHE P06276 2/20 0.75
LMNA P02545 2/20 0.75
PLIN1 O60240 1/20 0.75
TNFRSF1A P19438 1/20 0.75
ACHE P22303 1/20 0.75
RECQL P46063 1/20 0.75
PLIN5 Q00G26 1/20 0.75
ABHD5 Q8WTS1 1/20 0.75
MAOA P21397 4/20 0.72
RAB9A P51151 3/20 0.72
POLB P06746 1/20 0.72
NFKB1 P19838 2/20 0.71
NFKB2 Q00653 2/20 0.71
RELA Q04206 2/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL76030 1.00 MAPT (1.00) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL6200952 1.00 MAPT (1.00) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL27977352 0.95 MAPT (0.90) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL23789072 0.93 MAPT (0.87) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL7193506 0.93 CYP1B1 (1.00) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL77498 0.93 CYP1B1 (1.00) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL12533800 0.91 MAPT (0.82) MAPTCYP3A4ALDH1A1HPGDCYP1B1
4,4'-Dimethylchalcone SCHEMBL979560 0.90 MAPT (1.00) MAPTCYP3A4ALDH1A1HPGDCYP1B1
4,4'-Dimethylchalcone SCHEMBL979559 0.90 MAPT (1.00) MAPTCYP3A4ALDH1A1HPGDCYP1B1
SCHEMBL9915665 0.90 CYP1B1 (0.91) MAPTCYP3A4ALDH1A1HPGDCYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12576396-B2 Polynorbornene/carbon black-cross-linked three-dimensional network-immobilized copper/gold (PNBI/CB-Cu/Au) nanocatalyst, and preparation method and use thereof Hubei Engineering University (CN) 2026-03-17 US claimed
CN-119504491-A Efficient preparation method and application of optically pure beta-cyano ketone 哈尔滨理工大学 2025-02-25 CN claimed
US-20240261768-A1 POLYNORBORNENE/CARBON BLACK-CROSS-LINKED THREE-DIMENSIONAL NETWORK-IMMOBILIZED COPPER/GOLD (PNBI/CB-Cu/Au) NANOCATALYST, AND PREPARATION METHOD AND USE THEREOF Hubei Engineering University (CN) 2024-08-08 US claimed
CN-114797976-B Preparation and application of crosslinked norbornene copolymer/carbon black three-dimensional network immobilized bimetallic copper/gold nano catalyst 湖北工程学院 2023-11-17 CN claimed
WO-2023206835-A1 CROSS-LINKED NORBORNENE COPOLYMER/CARBON BLACK THREE-DIMENSIONAL NETWORK IMMOBILIZED BIMETALLIC COPPER/GOLD NANO-CATALYST, AND PREPARATION METHOD THEREFOR AND USE THEREOF 湖北工程学院 2023-11-02 WO claimed
CN-115141621-A Oil-based fracturing fluid, multi-stage fracturing method and method for online monitoring productivity of reservoir intervals 中国石油化工股份有限公司 2022-10-04 CN claimed
CN-113243610-B Acid and alkali resistant safety shoe with sole and preparation method thereof 温州市巨伦鞋业有限公司 2022-07-29 CN claimed
CN-113243610-A Acid and alkali resistant safety shoe with sole and preparation method thereof 温州市巨伦鞋业有限公司 2021-08-13 CN claimed
CN-107129499-B Fused heterocycle compounds of imidazole ring-containing and its preparation method and application 浙江工业大学 2019-04-09 CN claimed
CN-107129499-A Fused heterocycle compounds of imidazole ring-containing and its preparation method and application 浙江工业大学 2017-09-05 CN claimed
CN-104030984-B A kind of preparation method of pyrazole derivatives 甘肃农业大学 2016-07-13 CN claimed
CN-104030870-B A kind of preparation method of beta-cyano ketone NORTHWEST NORMAL UNIVERSITY (CN) 2015-10-28 CN claimed
CN-104860854-A Method for synthesizing beta-thiocarbonyl compound by taking Bunte salt as sulfur source UNIV NANJING SCIENCE & TECH 2015-08-26 CN claimed
CN-104030984-A Method for preparing pyrazole derivative UNIV NORTHWEST NORMAL 2014-09-10 CN claimed
CN-104030870-A Method for preparing beta-cyan ketone UNIV NORTHWEST NORMAL 2014-09-10 CN claimed
US-12576396-B2 Polynorbornene/carbon black-cross-linked three-dimensional network-immobilized copper/gold (PNBI/CB-Cu/Au) nanocatalyst, and preparation method and use thereof Hubei Engineering University (CN) 2026-03-17 US disclosed
CN-119504491-A Efficient preparation method and application of optically pure beta-cyano ketone 哈尔滨理工大学 2025-02-25 CN disclosed
US-4172955-A REARRANGMENT OF A CINNAMALDEHYDE TO A PHENYLMALONDIALDEHYDE TETRAMETHYL DISACETAL EMERY INDUSTRIES, INC. (US) 1979-10-30 US disclosed
EP-0004624-A2 Chromanon derivatives, process for their preparation, and their use as medicines and growth-promoting agents BAYER AG (DE) 1979-10-17 EP disclosed
US-4067823-A Thallium(III) reagents supported on montmorillonite clay minerals and oxythallation processes for utilizing same EMERY INDUSTRIES, INC. (US) 1978-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240261768-A1 POLYNORBORNENE/CARBON BLACK-CROSS-LINKED THREE-DIMENSIONAL NETWORK-IMMOBILIZED COPPER/GOLD (PNBI/CB-Cu/Au) NANOCATALYST, AND PREPARATION METHOD AND USE THEREOF AOC3, PNN, RPL23A MAPT 1563/4885CYP3A4 1430/4885ALDH1A1 399/4885
US-12576396-B2 Polynorbornene/carbon black-cross-linked three-dimensional network-immobilized copper/gold (PNBI/CB-Cu/Au) nanocatalyst, and preparation method and use thereof AOC3, PNN, SOD3 MAPT 1217/4885CYP3A4 1739/4885ALDH1A1 212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.