SCHEMBL1253443

SCHEMBL1253443

O=C(N(O)C(=O)C(F)(F)F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.33
CHRM2 P08172 2/20 0.31
CHRM4 P08173 2/20 0.31
CHRM5 P08912 2/20 0.31
CHRM1 P11229 2/20 0.31
CHRM3 P20309 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28569018 0.73
SCHEMBL2804056 0.71
SCHEMBL27096235 0.71 CA2 (0.33) CA2CHRM2CHRM4CHRM5CHRM1
SCHEMBL28877293 0.69
SCHEMBL9116954 0.69 CA2 (0.32) CA2
SCHEMBL29137569 0.69
SCHEMBL4421272 0.69 CA2 (0.32) CA2
SCHEMBL22183107 0.69 CA2 (0.32) CA2CHRM2CHRM4CHRM5CHRM1
SCHEMBL22183109 0.69 CA2 (0.32) CA2
SCHEMBL8669575 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7255808-B2 Functional fluid compositions containing erosion inhibitors SOLUTIA, INC. (US) 2007-08-14 US claimed
EP-1558716-A1 FUNCTIONAL FLUID COMPOSITIONS CONTAINING EROSION INHIBITORS Solutia Inc. (US) 2005-08-03 EP claimed
US-20050056809-A1 Functional fluid compositions containing erosion inhibitors SOLUTIA INC. 2005-03-17 US claimed
WO-2004041978-A1 FUNCTIONAL FLUID COMPOSITIONS CONTAINING EROSION INHIBITORS SOLUTIA INC. (US) 2004-05-21 WO claimed
WO-2023209191-A1 PREP BINDING LIGANDS UNIVERSITY OF HELSINKI (FI) 2023-11-02 WO disclosed
EP-4133062-A1 COMPOSITION AND METHOD FOR INACTIVATING A VIRUS Rnassist Limited (GB) 2023-02-15 EP disclosed
EP-3294452-A1 PYROLYTIC METHOD FOR THE PRODUCTION OF PARTICLES CONTAINING AT LEAST ONE METAL SPECIES Fraunhofer Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2018-03-21 EP disclosed
EP-2961268-A1 SAMPLE FIXATION AND STABILISATION Goldsborough, Andrew Simon (FR) 2016-01-06 EP disclosed
WO-2014131906-A1 SAMPLE FIXATION AND STABILISATION GOLDSBOROUGH ANDREW SIMON (FR) 2014-09-04 WO disclosed
US-8557782-B2 Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-10-15 US disclosed
EP-2024352-B1 GLUCOPYRANOSYL-SUBSTITUTED BENZONITRILE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE BOEHRINGER INGELHEIM INT (DE) 2013-04-24 EP disclosed
EP-1989191-B1 GLUCOPYRANOSYL-SUBSTITUTED BENZONITRILE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR MANUFACTURE BOEHRINGER INGELHEIM INT (DE) 2011-07-20 EP disclosed
US-20050056809-A1 Functional fluid compositions containing erosion inhibitors SOLUTIA INC. 2005-03-17 US disclosed
WO-2004085457-A2 17BETA-HYDROXYSTEROID DEHYDROGENASE INHIBITORS STERIX LIMITED (GB) 2004-10-07 WO disclosed
WO-2004041978-A1 FUNCTIONAL FLUID COMPOSITIONS CONTAINING EROSION INHIBITORS SOLUTIA INC. (US) 2004-05-21 WO disclosed
US-5840917-A ADMINISTERING TO MAMMAL TO ERADICATE HELICOBACTER PYLORI TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-11-24 US disclosed
US-4394386-A Fluorinated carbamate insecticides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-07-19 US disclosed
US-4393074-A Fluorinated carbamate insecticides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-07-12 US disclosed
US-4323578-A Fluorinated carbamate insecticides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-04-06 US disclosed
EP-0026569-A1 Fluorinated carbamates, processes for their preparation, insecticidal compositions comprising them, and controlling insects thereby E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-04-08 EP disclosed