SCHEMBL8669575

SCHEMBL8669575

O=C(N([SiH3])[SiH3])C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trimethylammonium SCHEMBL28067620 0.73 CHRM2 (0.34)
SCHEMBL27821515 0.69 CHRM2 (0.34)
SCHEMBL27096235 0.69 CA2 (0.33)
SCHEMBL1253443 0.69 CA2 (0.33)
SCHEMBL2804056 0.69
SCHEMBL28877293 0.67
SCHEMBL29137569 0.67
SCHEMBL22183109 0.67 CA2 (0.32)
SCHEMBL22183107 0.67 CA2 (0.32)
SCHEMBL9116954 0.67 CA2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0138403-B1 PROCESS FOR PREPARING PHOSPHINIC ACID INTERMEDIATES E.R. Squibb &amp; Sons, Inc. (US) 1989-03-15 EP claimed
US-4602092-A Method for making phosphinic acid intermediates E. R. SQUIBB & SONS, INC. (US) 1986-07-22 US claimed
US-4594199-A Method for making phosphinic acid intermediates E. R. SQUIBB & SONS, INC. (US) 1986-06-10 US claimed
EP-0138403-A2 Process for preparing phosphinic acid intermediates E.R. Squibb &amp; Sons, Inc. (US) 1985-04-24 EP claimed
EP-0593368-B1 Process for preparing a hypocaloric soluble glucose polymer ROQUETTE FRERES (FR) 1998-12-09 EP disclosed
US-5424418-A Predominantly composed of 1-6 bonds; subjected to hydrogenation and molecular sieving stages ROQUETTE FRERES (FR) 1995-06-13 US disclosed
EP-0593368-A1 Hypocaloric soluble glucose polymer and process for preparing the same Roquette Frˬres (FR) 1994-04-20 EP disclosed
EP-0138403-B1 PROCESS FOR PREPARING PHOSPHINIC ACID INTERMEDIATES E.R. Squibb &amp; Sons, Inc. (US) 1989-03-15 EP disclosed
US-4602092-A Method for making phosphinic acid intermediates E. R. SQUIBB & SONS, INC. (US) 1986-07-22 US disclosed
US-4594199-A Method for making phosphinic acid intermediates E. R. SQUIBB & SONS, INC. (US) 1986-06-10 US disclosed
EP-0138403-A2 Process for preparing phosphinic acid intermediates E.R. Squibb &amp; Sons, Inc. (US) 1985-04-24 EP disclosed