⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12534734 | 0.88 | CRHR1 (0.32) | — | |
| SCHEMBL1636123 | 0.85 | CHRM3 (0.31) | — | |
| SCHEMBL1636162 | 0.85 | KHK (0.40) | — | |
| SCHEMBL12534748 | 0.83 | LRRK2 (0.32) | — | |
| SCHEMBL12534820 | 0.82 | CRHR1 (0.33) | — | |
| SCHEMBL12534724 | 0.82 | CRHR1 (0.39) | — | |
| SCHEMBL12534825 | 0.80 | CRHR1 (0.33) | — | |
| SCHEMBL12534741 | 0.78 | CRHR1 (0.37) | — | |
| SCHEMBL12534767 | 0.76 | CRHR1 (0.35) | — | |
| SCHEMBL1636782 | 0.76 | KHK (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455511-B2 | Pyrrolopyridine derivatives substituted with cyclic amino group | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2013-06-04 | — | — | US | disclosed |
| US-20110130364-A1 | PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH CYCLIC AMINO GROUP | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-06-02 | — | — | US | disclosed |
| US-7932259-B2 | Pyrrolo[2,3-d]pyrimidine derivatives substituted with a cyclic amino group | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-04-26 | — | — | US | disclosed |
| US-20080287397-A1 | Pyrrolopyrimidine Derivatives Substituted with Cyclic Amino Group | TASHO PHARMACEUTICAL CO., LTD. (JP) | 2008-11-20 | — | — | US | disclosed |