Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 5/20 | 0.45 |
| ▸ | PRCP | P42785 | 12/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.41 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12536334 | 0.94 | MC4R (0.45) | MC4RPRCPMC3R | |
| SCHEMBL12536329 | 0.94 | MC4R (0.45) | MC4RPRCPMC3R | |
| SCHEMBL15016243 | 0.94 | MC4R (0.47) | MC4RPRCPMC3R | |
| SCHEMBL12536314 | 0.92 | MC4R (0.39) | MC4RPRCPSLC6A9MC3R | |
| SCHEMBL13493146 | 0.92 | MC4R (0.44) | MC4RPRCPMC3RNTRK1 | |
| SCHEMBL12536508 | 0.92 | MC4R (0.44) | MC4RPRCPMC3RNTRK1 | |
| SCHEMBL12536408 | 0.92 | MC4R (0.44) | MC4RPRCPMC3RNTRK1 | |
| SCHEMBL1919675 | 0.92 | MC4R (0.45) | MC4RPRCPMC3RNTRK1 | |
| SCHEMBL1919620 | 0.92 | MC4R (0.44) | MC4RPRCPMC3RNTRK1 | |
| SCHEMBL12536533 | 0.90 | PRCP (0.43) | MC4RPRCPMC3RNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110136814-A1 | Diazepine and Diazocane Compounds As MC4 Agonists | ANDREWS MARK DAVID | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136814-A1 | Diazepine and Diazocane Compounds As MC4 Agonists | MC4R, CHRM4, GPR4 | MC4R 1/4885PRCP 2814/4885SLC6A9 2638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.